PDGFRA activating mutations in gastrointestinal stromal tumors.
about
Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]A reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor αActivation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independentMolecular biology of lung cancer: clinical implicationsA census of human cancer genesDiscovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndromeCombined surgical and molecular therapy: the gastrointestinal stromal tumor modelBRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targetsInhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cellsOverexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progressionGenetic alteration and mutation profiling of circulating cell-free tumor DNA (cfDNA) for diagnosis and targeted therapy of gastrointestinal stromal tumorsTargeting gastrointestinal stromal tumors: the role of regorafenibClinicopathological significance of c-KIT mutation in gastrointestinal stromal tumors: a systematic review and meta-analysisRecurrent retroperitoneal extra-GIST with rhabdomyosarcomatous and chondrosarcomatous differentiations: a rare case and literature reviewEmerging Agents for the Treatment of Advanced, Imatinib-Resistant Gastrointestinal Stromal Tumors: Current Status and Future DirectionsPersonalized Medicine in Gastrointestinal Stromal Tumor (GIST): Clinical Implications of the Somatic and Germline DNA AnalysisMyxoid epithelioid gastrointestinal stromal tumor harboring an unreported PDGFRA mutation: report of a case and review of the literatureEndoscopic treatment for gastrointestinal stromal tumor: Advantages and hurdlesPazopanib in sarcomas: expanding the PALETTEThe GIST of targeted therapy for malignant melanomaA young man with primary prostatic extra-gastrointestinal stromal tumor: a rare case report and review of the literatureTargeting molecular addictions in cancerStructural and functional properties of platelet-derived growth factor and stem cell factor receptorsClinical practice guidelines for patients with gastrointestinal stromal tumor in TaiwanBeyond the GIST: mesenchymal tumors of the stomachA great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential.Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumorUpdate on clinical research and state of the art management of patients with advanced sarcomas and GISTSunitinib in solid tumorsAdvanced gastrointestinal stromal tumor in Europe: a review of updated treatment recommendationsCurrent management and prognostic features for gastrointestinal stromal tumor (GIST)Core-shell hydrogel particles harvest, concentrate and preserve labile low abundance biomarkersp53 modulation as a therapeutic strategy in gastrointestinal stromal tumorsTMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including gliomaStromal, fibrous, and fatty gastrointestinal tumors in a patient with a PDGFRA gene mutationGenome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatismRole of platelet-derived growth factors in physiology and medicinePI3K pathway alterations in cancer: variations on a themeEffect of sunitinib on metastatic gastrointestinal stromal tumor in patients with neurofibromatosis type 1: a case report.Rare cystic liver lesions: a diagnostic and managing challenge.
P2860
Q21133528-348BD645-25F3-4124-8B82-E9CAB74123A0Q24339412-7315CCA6-152A-4D6A-B6C9-A8A26A2BB09AQ24545984-C4C25F03-39E0-4654-B554-9262EBE18F13Q24610335-A992AD56-DF03-40A9-9E35-72E28B7D4A52Q24647081-F29E3A0D-8F06-4BC3-9846-E71DF6106F5CQ24670121-9D485FE7-CDF8-428B-B357-D0036103FAFAQ24675987-AAA8511B-F596-42D8-8BC0-C3738E591B29Q24685106-0CFD8DB9-869C-4DE5-BCE5-F9B97BBE516AQ24810622-CE145122-73EC-48D6-A08D-1ACAB5B8C098Q24813774-5724432F-EBC4-4354-BFDF-7DF5DF222FA0Q26738567-310808A5-2D14-470E-AC59-F44686FD65A5Q26747162-E7B038FE-F613-46BA-AD9F-896971778098Q26782641-A0E157EA-9915-4511-945B-A5E15E624A77Q26783437-3D6F8C43-D8A8-4903-8341-8595D37786E3Q26799387-9E20FA9B-77E3-481C-9346-89A5CAE86221Q26800005-07D9333A-2132-47C7-932F-C6793B8035EDQ26801942-08867B6B-B390-4D1E-8927-86336A02D9F6Q26822890-F41D0101-0B4C-46B5-BE8D-2E70E73C60FCQ26825050-8F15E7A4-32F5-456F-8300-B477B7354162Q26827092-0881889B-182A-483F-8617-83F9597FD614Q26827469-D1B7C64A-4CB1-457C-912E-4F3FBAEA8E4DQ26829525-BBB8931A-3F4A-4A52-B5DA-904FF7A7A37CQ26829546-2D34229A-8450-49BE-B28F-1D20299E5FAFQ27027632-FB7C7FEF-328A-4880-988B-FE2FDEC96063Q27028116-03CAE168-216D-45B3-A7C1-34B9C610FA9BQ27824814-1D7EEBBF-74CD-4530-BC32-20955ECFC56BQ27851455-A30C7608-3E57-4F98-B6DE-E3A117C8855CQ28073290-AC85FFA3-C558-4F07-A3FA-AA376A3356F7Q28245467-739F5AD5-B7D6-49BF-8106-2EEC79EDC2CFQ28247449-4C0FF3A4-C92A-4C3E-92B0-AB1005D50534Q28391684-F82D358C-A76E-42B7-9890-026798666F13Q28474977-C54EC581-895F-4864-9956-0CFF6C3B7AC4Q28483922-16FFC40E-C629-4891-AA9F-23B10704E4B3Q28740616-2F87FF4F-82FC-4900-82BB-DA4AFCD6D5F0Q28742442-E5B63FB4-8341-4617-A9DF-A99FC98D19C5Q28943360-EC612805-F74D-497F-A16E-B907E8781FCBQ29615222-418F93BD-E987-4C45-87DC-170A2F1146F3Q29615530-4BBCAA3B-33FE-4AD2-8088-D7259FCC589AQ30431506-C93598D4-7A65-4C3E-A868-E892A8DD93A5Q30446819-ECB3C2BC-5E66-4105-831C-77CC3694DE39
P2860
PDGFRA activating mutations in gastrointestinal stromal tumors.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
PDGFRA activating mutations in gastrointestinal stromal tumors.
@ast
PDGFRA activating mutations in gastrointestinal stromal tumors.
@en
PDGFRA activating mutations in gastrointestinal stromal tumors.
@nl
type
label
PDGFRA activating mutations in gastrointestinal stromal tumors.
@ast
PDGFRA activating mutations in gastrointestinal stromal tumors.
@en
PDGFRA activating mutations in gastrointestinal stromal tumors.
@nl
prefLabel
PDGFRA activating mutations in gastrointestinal stromal tumors.
@ast
PDGFRA activating mutations in gastrointestinal stromal tumors.
@en
PDGFRA activating mutations in gastrointestinal stromal tumors.
@nl
P2093
P50
P356
P1433
P1476
PDGFRA activating mutations in gastrointestinal stromal tumors
@en
P2093
Andrea Haley
Chang-Jie Chen
Christopher D M Fletcher
Christopher L Corless
Diana J Griffith
George D Demetri
Jonathan A Fletcher
Laura McGreevey
Nora Joseph
P304
P356
10.1126/SCIENCE.1079666
P407
P577
2003-01-09T00:00:00Z