MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state. - Wikidata - wikimedia - TriplyDB

MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state.

MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state.

http://www.wikidata.org/entity/Q34170278

about

Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?Data submission and quality in microarray-based microRNA profiling Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells The biomarkers of immune dysregulation and inflammation response in Parkinson disease MicroRNA (miRNA): sequence and stability, viroid-like properties, and disease association in the CNS MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune Response Up-Regulation of miRNA-146a in Progressive, Age-Related Inflammatory Neurodegenerative Disorders of the Human CNS Involvement of microRNA in microglia-mediated immune response Microglia centered pathogenesis in ALS: insights in cell interconnectivity Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice MicroRNAs in the Host Response to Viral Infections of Veterinary Importance Increased microRNA-146a levels in plasma of patients with newly diagnosed type 2 diabetes mellitus Evolution of microRNA (miRNA) Structure and Function in Plants and Animals: Relevance to Aging and Disease Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders Cell-type-specific Jumonji histone demethylase gene expression in the healthy rat CNS: detection by a novel flow cytometry method.MiR-155 induction in microglial cells suppresses Japanese encephalitis virus replication and negatively modulates innate immune responses.A genome-wide survey for prion-regulated miRNAs associated with cholesterol homeostasis Characterization of microRNAs in mud crab Scylla paramamosain under Vibrio parahaemolyticus infection.MicroRNA-146a represses mycobacteria-induced inflammatory response and facilitates bacterial replication via targeting IRAK-1 and TRAF-6.Differential expression profiling of spleen microRNAs in response to two distinct type II interferons in Tetraodon nigroviridis.miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells.Identification of endogenous reference genes for the analysis of microRNA expression in the hippocampus of the pilocarpine-induced model of mesial temporal lobe epilepsy Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD)Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways.Studying micro RNA Function and Dysfunction in Alzheimer's Disease Regnase-1 in microglia negatively regulates high mobility group box 1-mediated inflammation and neuronal injury.Epigenetics and the modulation of neuroinflammation.Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell death MiRNA expression profiles in the brains of mice infected with scrapie agents 139A, ME7 and S15.MicroRNAs in the brain: it's regulatory role in neuroinflammation.Prion disease and the innate immune system.Small RNA drugs for prion disease: a new frontier.Reciprocal effects of Toll-like receptors and miRNAs on biological processes in human health and disease: a systematic review.Microdissection and transcriptional profiling: a window into the pathobiology of preclinical prion disease.Roles of microglia in brain development, tissue maintenance and repair.miR-146a-5p Antagonized AGEs- and P.g-LPS-Induced ABCA1 and ABCG1 Dysregulation in Macrophages via IRAK-1 Downregulation.Toll-like receptor 2 deficiency shifts PrP106-126-induced microglial activation from a neurotoxic to a neuroprotective phenotype.Role of Microglia in Neurological Disorders and Their Potentials as a Therapeutic Target.Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization.miRNAs as biomarkers of neurodegenerative disorders.

P2860

Q21129257-8E258487-71A0-41FE-888B-20AF9E4D4AE9 Q24282608-52A9BEB5-EB48-425B-9821-0E0058E460FA Q24607278-A6CC88E9-7E51-41EF-87F7-519005DD0A94 Q26738459-DEE2BD56-AE4F-4895-A539-2773B851868E Q26825514-FAC5DC47-A862-4D35-BDF7-84816070963D Q26830890-C1209DA6-E49B-4D43-AC45-F358A715E531 Q26851364-20061CA5-3714-4663-9BC1-260AD91AF747 Q26851399-8110EAE4-D467-4325-BF68-0F89ADED2E06 Q27009559-487F26E4-E44F-4D72-A883-8FBD273B4F3F Q27340506-D3134768-BB2C-466B-95BB-6471CCBFD195 Q28078710-D0CADE08-E9D4-4FA0-A293-B432016C4A84 Q28536498-5923E036-3D58-4568-9501-61917ED51216 Q28647645-80A707D1-4A72-44D2-95C3-1194E1A51492 Q30656632-106AB5EB-4E0C-4973-AEE5-6FD592112D09 Q33668369-A6D6FD2B-DB35-4EB5-BA12-4D35099B211C Q33729909-F5E40D4B-9681-48D6-8589-320CEE8963B9 Q34416679-327D750D-A931-452A-B5CF-55B332A79353 Q34983725-78FD2A02-6814-49E3-835D-B9B9E450EEF9 Q35072509-60C7A600-4555-44A2-8509-597862F3FB9B Q35163626-A66CA66E-8AE9-4A6C-924C-76A759E2D8D1 Q35164604-745FBC37-6F3B-4C72-92B9-5C308013073C Q35194710-1EB63D83-AF03-43B9-80C9-B29711297D9C Q35887465-1CB13FC6-A8B3-4D61-BAF4-6A92FB5E7ACB Q36383975-AE277BEC-4129-449F-8313-E20C34709ED6 Q36589571-0881C0A8-3707-4F75-ACF0-852718E9003E Q36764867-35CE8EE3-7819-4CB5-903B-DB67DA1B2CBF Q37249157-CC4C9BD3-DC2C-480D-936A-B0AE539DE248 Q37424055-A10EA338-8AE3-4E74-8184-7ACEA73B45E0 Q37489927-2582FB1D-32EB-490F-A9C0-39C4E502E674 Q38073708-554AED38-99A1-41D5-A3E7-60114C8E4592 Q38076137-9438DD6C-BD5C-479A-8B13-D3C67A38BADE Q38121120-C266D9BB-DCD5-4478-995E-8E6F73EE4E18 Q38148590-00BF2E04-42F5-4044-BB07-E88ED49A6928 Q38177082-1AFC84DB-1D95-44A5-A33B-15F2F3E155C8 Q38396105-8C905C28-4B3B-43BD-8565-E8FBC5D71C07 Q38895580-FD728D26-D62E-4DD9-89A3-4CE725B85E7E Q38946510-1FBE70D8-0545-4FCA-827E-DD6C6737D163 Q39004244-0550756D-84AB-479F-A932-390630734C47 Q39016000-FB238412-B314-47C5-8C04-908F606F2103 Q39104808-C9436250-BE50-416D-88DF-1AE408A859E7

P2860

MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state.

http://www.wikidata.org/entity/Q34170278

description

2012 nî lūn-bûn

@nan

2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

MicroRNA 146a (miR-146a) is ov ...... e microglial activation state.

@ast

MicroRNA 146a (miR-146a) is ov ...... e microglial activation state.

@en

MicroRNA 146a

@nl

type

label

MicroRNA 146a (miR-146a) is ov ...... e microglial activation state.

@ast

MicroRNA 146a (miR-146a) is ov ...... e microglial activation state.

@en

MicroRNA 146a

@nl

prefLabel

MicroRNA 146a (miR-146a) is ov ...... e microglial activation state.

@ast

MicroRNA 146a (miR-146a) is ov ...... e microglial activation state.

@en

MicroRNA 146a

@nl

P1433

Q34170278-0BB882A2-20BE-4353-9029-FE25D60885F7

P1476

Q34170278-CC82D59F-E741-4802-B9E3-890F5C531942

P2093

Q34170278-0E48D72E-737A-4FBB-8574-02A65922BFDD

Q34170278-45198171-B4A7-4E8C-9651-A1CE29FD8CD5

Q34170278-5EFDF326-A0C1-435E-8330-3C73D7215326

Q34170278-6276AC12-F6AE-4431-BF41-8B72D6701744

Q34170278-6F03BB6F-8131-46E9-961A-093664D12D1E

Q34170278-81D31712-54B6-4A5E-B6E2-7C70C3F6B6B9

Q34170278-A1227CA0-0F70-468A-8A05-12DB2C1DDE21

P2860

Q34170278-005714CC-9B7A-4E53-9573-41A72DB3DB9B

Q34170278-0A68B0D6-BDBD-457A-9D8A-5B9C2580559F

Q34170278-15F15398-10F8-47AE-9E46-A8A2E10E018F

Q34170278-173A1E4C-47B2-4CF1-BC82-2423B1352034

Q34170278-32F44D3A-3285-4B11-9438-F768F5AEE455

Q34170278-3347ED6D-2790-48C2-867F-EA51530DE209

Q34170278-39DCB1D3-6B09-47EE-BC8D-252E2D44F941

Q34170278-3EE634E5-02C4-4152-84F3-97CF06D2CC95

Q34170278-434EEE29-1BB3-442A-9249-6D4DA9B5EAED

Q34170278-48845F67-3FCE-4535-B062-C5006B1A2226

P304

Q34170278-70550365-34A2-467B-A15E-F88274697209

P31

Q34170278-CA5D8239-E344-45EE-A207-67360DFFC3B4

P356

Q34170278-5EF2B408-9DE9-492D-87C3-B76ED102D5F1

P407

Q34170278-6C2058F0-8FB9-442B-BEBD-DF7085C8686F

P433

Q34170278-61BA4726-C7E9-4A94-8413-81AC30FBE893

P478

Q34170278-1454D823-FA5B-434C-95F8-95D957814382

P577

Q34170278-D1F5BF61-D4A5-48BF-9E1E-977172D87DD3

P5875

Q34170278-DAE3857F-AA7C-45DE-B162-9C7EF84326FE

P698

Q34170278-B3AA4415-81EF-46D2-94F9-B5A22FEA48FA

P921

Q34170278-C18EA0C1-8BD7-4218-B50B-E80F0433E437

Q34170278-EBC061BD-E20F-494B-8729-EF3F3FC6E357

Q34170278-FFBED5A2-BC81-4644-9755-93A50208C7D8

P932

Q34170278-7F1A2E1B-7B5F-4CC4-9091-71FB9A4E32E4

P356

JOURNAL.PONE.0030832

P1433

P1476

MicroRNA 146a (miR-146a) is ov ...... e microglial activation state.

@en

P2093

Catherine Robertson

http://www.w3.org/2001/XMLSchema#string

Kathy Manguiat

http://www.w3.org/2001/XMLSchema#string

Reuben Saba

http://www.w3.org/2001/XMLSchema#string

Rhiannon L C H Huzarewich

http://www.w3.org/2001/XMLSchema#string

Sarah Medina

http://www.w3.org/2001/XMLSchema#string

Shantel Gushue

http://www.w3.org/2001/XMLSchema#string

Stephanie A Booth

http://www.w3.org/2001/XMLSchema#string

P2860

A miRNA signature of prion induced neurodegeneration

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Toll-like receptor signalling

miR-221 suppresses ICAM-1 translation and regulates interferon-gamma-induced ICAM-1 expression in human cholangiocytes

Significance analysis of microarrays applied to the ionizing radiation response

MicroRNAs: target recognition and regulatory functions

HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling

The impact of microRNAs on protein output

P304

e30832

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0030832

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P577

2012-02-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

221859779

http://www.w3.org/2001/XMLSchema#string

P698

22363497

http://www.w3.org/2001/XMLSchema#string

P921

Prion protein family

P932

3281888

http://www.w3.org/2001/XMLSchema#string