The macro domain protein family: structure, functions, and their potential therapeutic implications.
about
BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic propertiesBacterial pathogens commandeer Rab GTPases to establish intracellular nichesThe role of ADP-ribosylation in regulating DNA interstrand crosslink repairADP-ribosyltransferases and poly ADP-ribosylationHistone variants: dynamic punctuation in transcription.Histone variants: emerging players in cancer biology.The hepatitis E virus polyproline region is involved in viral adaptationHepatitis E virus inhibits type I interferon induction by ORF1 productsTransition-state analysis of 2-O-acetyl-ADP-ribose hydrolysis by human macrodomain 1.Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair.MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones.The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitisAn LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaksThe PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response.Histone H2A variants in nucleosomes and chromatin: more or less stable?Viral Macro Domains Reverse Protein ADP-Ribosylation.The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection.CHD1L: a novel oncogene.Metabolic sensors and their interplay with cell signalling and transcription.Macro domains as metabolite sensors on chromatin.NAD and ADP-ribose metabolism in mitochondria.ADP-ribosylation: activation, recognition, and removalHepatitis E virus ORF1 encoded macro domain protein interacts with light chain subunit of human ferritin and inhibits its secretion.NMR study of non-structural proteins-part III: (1)H, (13)C, (15)N backbone and side-chain resonance assignment of macro domain from Chikungunya virus (CHIKV).Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning.NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV).Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.Combined computational and experimental analysis of a complex of ribonuclease III and the regulatory macrodomain protein, YmdBDiscovery of a selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerases 14.NMR study of non-structural proteins--part II: (1)H, (13)C, (15)N backbone and side-chain resonance assignment of macro domain from Venezuelan equine encephalitis virus (VEEV).Genetic host specificity of hepatitis E virus.Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis.A macrodomain-linked immunosorbent assay (MLISA) for mono-ADP-ribosyltransferases.The role of poly ADP-ribosylation in the first wave of DNA damage response.Geometrical constraints limiting the poly(ADP-ribose) conformation investigated by molecular dynamics simulation.Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.
P2860
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P2860
The macro domain protein family: structure, functions, and their potential therapeutic implications.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The macro domain protein famil ...... tial therapeutic implications.
@ast
The macro domain protein famil ...... tial therapeutic implications.
@en
The macro domain protein famil ...... tial therapeutic implications.
@nl
type
label
The macro domain protein famil ...... tial therapeutic implications.
@ast
The macro domain protein famil ...... tial therapeutic implications.
@en
The macro domain protein famil ...... tial therapeutic implications.
@nl
prefLabel
The macro domain protein famil ...... tial therapeutic implications.
@ast
The macro domain protein famil ...... tial therapeutic implications.
@en
The macro domain protein famil ...... tial therapeutic implications.
@nl
P2093
P1433
P1476
The macro domain protein famil ...... tial therapeutic implications.
@en
P2093
Weidong Han
Xiaobing Fu
Xiaolei Li
P304
P356
10.1016/J.MRREV.2011.03.001
P407
P577
2011-03-21T00:00:00Z