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Spatial range of autocrine signaling: modeling and computational analysis.

Spatial range of autocrine signaling: modeling and computational analysis.

http://www.wikidata.org/entity/Q34176460

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Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity Cell surface concentrations and concentration ranges for testing in vitro autocrine loops and small molecules Collective migration of an epithelial monolayer in response to a model wound Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model.Cardiomyocyte hypertrophy and degradation of connexin43 through spatially restricted autocrine/paracrine heparin-binding EGF Microfluidic perfusion for regulating diffusible signaling in stem cells.Long-range signal transmission in autocrine relays.Stochastic model of autocrine and paracrine signals in cell culture assays Self-organization of polarized cell signaling via autocrine circuits: computational model analysis.Ligand accumulation in autocrine cell cultures.Quantitative understanding of cell signaling: the importance of membrane organization.Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis.Balancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback.Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: incorporating EGFR signaling pathway and angiogenesis Computational modeling of extracellular mechanotransduction.Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.A computational framework for the topological analysis and targeted disruption of signal transduction networks.Subcellular resolution mapping of endogenous cytokine secretion by nano-plasmonic-resonator sensor array Array feature size influences nucleic acid surface capture in DNA microarrays Time and length scales of autocrine signals in three dimensions.Design principles of cell circuits with paradoxical components.Autocrine epidermal growth factor signaling stimulates directionally persistent mammary epithelial cell migration Coarse-grained molecular simulation of diffusion and reaction kinetics in a crowded virtual cytoplasm.A computational kinetic model of diffusion for molecular systems.Models at the single cell level.Pattern, growth, and control.Mechanotransduction through growth-factor shedding into the extracellular space Computational model and microfluidic platform for the investigation of paracrine and autocrine signaling in mouse embryonic stem cells.Oscillatory flow accelerates autocrine signaling due to nonlinear effect of convection on receptor-related actions.Effects of convective transport on chemical signal propagation in epithelia Equilibrium and dynamic design principles for binding molecules engineered for reagentless biosensors.Secreting and sensing the same molecule allows cells to achieve versatile social behaviors Simulating non-small cell lung cancer with a multiscale agent-based model.Autocrine production of insulin-like growth factor-I (IGF-I) affects paracellular transport across epithelial cells in vitro.ApoE-mediated cholesterol efflux from macrophages: separation of autocrine and paracrine effects.Mathematical modelling and computational study of two-dimensional and three-dimensional dynamics of receptor-ligand interactions in signalling response mechanisms.Allovalency revisited: an analysis of multisite phosphorylation and substrate rebinding.Model of competitive binding of vascular endothelial growth factor and placental growth factor to VEGF receptors on endothelial cells.Model of the initiation of signal transduction by ligands in a cell culture: simulation of molecules near a plane membrane comprising receptors.3D computation modelling of the influence of cytokine secretion on Th-cell development suggests that negative selection (inhibition of Th1 cells) is more effective than positive selection by IL-4 for Th2 cell dominance.

P2860

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P2860

Spatial range of autocrine signaling: modeling and computational analysis.

http://www.wikidata.org/entity/Q34176460

description

2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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Spatial range of autocrine signaling: modeling and computational analysis.

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Spatial range of autocrine signaling: modeling and computational analysis.

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Spatial range of autocrine signaling: modeling and computational analysis.

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Spatial range of autocrine signaling: modeling and computational analysis.

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Spatial range of autocrine signaling: modeling and computational analysis.

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Spatial range of autocrine signaling: modeling and computational analysis.

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Spatial range of autocrine signaling: modeling and computational analysis.

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D A Lauffenburger

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H S Wiley

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S Y Shvartsman

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P2860

Physics of chemoreception

Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing

Cell signaling by receptor tyrosine kinases

Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways

Single-particle tracking: applications to membrane dynamics

Real-time quantitative measurement of autocrine ligand binding indicates that autocrine loops are spatially localized.

Epidermal growth factor receptors: critical mediators of multiple receptor pathways.

Multiple positive and negative regulators of signaling by the EGF-receptor.

The epidermal growth factor receptor and its ligand family: their potential role in repair and remodelling in asthma.

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