GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome.
about
P1343
Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.Down syndrome and leukemia: insights into leukemogenesis and translational targetsThe biology of pediatric acute megakaryoblastic leukemiaAcute Erythroleukemias, Acute Megakaryoblastic Leukemias, and Reactive Mimics: A Guide to a Number of Perplexing EntitiesMyeloid leukemia in Down syndromeThe emerging role of GATA transcription factors in development and diseaseTransient Abnormal Myelopoiesis and AML in Down Syndrome: an UpdateTranscription factor GATA-1 and Down syndrome leukemogenesisCross-talk of GATA-1 and P-TEFb in megakaryocyte differentiation.The prenatal origins of cancerPerturbed hematopoiesis in the Tc1 mouse model of Down syndrome.A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder.Down syndrome and malignancies: a unique clinical relationship: a paper from the 2008 william beaumont hospital symposium on molecular pathologyGATA Transcription Factors and Cancer.Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.Leukaemia -- a developmental perspective.The use of mouse models for understanding the biology of down syndrome and agingEarly block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1.Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia.Origins of leukaemia in children with Down syndrome.Purification of leukemic blast cells from blood smears using laser microdissection.Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21Myeloid Proliferations Associated with Down Syndrome.Mosaic Trisomy 21 and Trisomy 14 as Acquired Cytogenetic Abnormalities without GATA1 Mutation in A Pediatric Non-Down Syndrome Acute Megakaryoblastic LeukemiaBaicalein antagonizes acute megakaryoblastic leukemia in vitro and in vivo by inducing cell cycle arrestHaematology of Down syndromeA novel mutation in the GATA1 gene associated with acute megakaryoblastic leukemia in a Korean Down syndrome patient.Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivoDevelopmental differences in IFN signaling affect GATA1s-induced megakaryocyte hyperproliferationInsights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndromeGATA1 mutations in a cohort of Malaysian children with Down syndrome-associated myeloid disorderGATA1-mediated transcriptional regulation of the γ-secretase activating protein increases Aβ formation in Down syndrome.Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes.The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapyMutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome.GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.Unique clinical and biological features of leukemia in Down syndrome children.The impact of trisomy 21 on foetal haematopoiesis.
P2860
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P2860
GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@ast
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@en
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@nl
type
label
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@ast
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@en
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@nl
prefLabel
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@ast
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@en
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@nl
P2093
P1433
P1476
GATA1 mutations in transient l ...... tic leukemia of Down syndrome.
@en
P2093
Alvin Zipursky
Johann K Hitzler
Joseph Cheung
P304
P356
10.1182/BLOOD-2003-01-0013
P407
P4510
P577
2003-02-13T00:00:00Z