Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation. - Wikidata - wikimedia - TriplyDB

Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.

Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.

http://www.wikidata.org/entity/Q34179395

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NMNAT1 mutations cause Leber congenital amaurosis New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology The purinergic neurotransmitter revisited: a single substance or multiple players?Redox control of glutamine utilization in cancer Regulation of cell survival and death by pyridine nucleotides Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment.The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications Sirtuin deacylases: a molecular link between metabolism and immunity Circadian regulation of metabolism NAMPT-mediated salvage synthesis of NAD+ controls morphofunctional changes of macrophages Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration Prediction of intracellular metabolic states from extracellular metabolomic data NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes Targeted, LCMS-based Metabolomics for Quantitative Measurement of NAD(+) Metabolites.Sirtuin catalysis and regulation Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues.Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues Sequence divergence and diversity suggests ongoing functional diversification of vertebrate NAD metabolism.Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae Dissecting systemic control of metabolism and aging in the NAD World: the importance of SIRT1 and NAMPT-mediated NAD biosynthesis.Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation.Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7 SARM1 activation triggers axon degeneration locally via NAD⁺ destruction Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo.NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes.NAD(+)/NADH and skeletal muscle mitochondrial adaptations to exercise.Salvage of nicotinamide adenine dinucleotide plays a critical role in the bioenergetic recovery of post-hypoxic cardiomyocytes.Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.Comparative Metabolomic Profiling Reveals That Dysregulated Glycolysis Stemming from Lack of Salvage NAD+ Biosynthesis Impairs Reproductive Development in Caenorhabditis elegans Generation, Release, and Uptake of the NAD Precursor Nicotinic Acid Riboside by Human Cells Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications.Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.

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P2860

Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.

http://www.wikidata.org/entity/Q34179395

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Pathways and subcellular compa ...... mitochondrial NAD generation.

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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type

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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Pathways and subcellular compa ...... mitochondrial NAD generation.

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Journal of Biological Chemistry

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Pathways and subcellular compa ...... o mitochondrial NAD generation

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Christian Dölle

http://www.w3.org/2001/XMLSchema#string

Marc Niere

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P2860

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein

Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism

Elevation of cellular NAD levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1

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Mathias Ziegler

Andrey Nikiforov

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