Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator. - Wikidata - wikimedia - TriplyDB

Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator.

Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator.

http://www.wikidata.org/entity/Q34180463

about

Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future prospects Current therapeutic developments in atrophic age-related macular degeneration Age-Related Macular Degeneration: Advances in Management and Diagnosis Retinol Dehydrogenases Regulate Vitamin A Metabolism for Visual Function Present and possible therapies for age-related macular degeneration.Rational Tuning of Visual Cycle Modulator Pharmacodynamics Quantitative autofluorescence and cell density maps of the human retinal pigment epithelium.Pharmacological inhibition of lipofuscin accumulation in the retina as a therapeutic strategy for dry AMD treatment.Update on current and future novel therapies for dry age-related macular degeneration.Dry age-related macular degeneration: A currently unmet clinical need.Phase ii, randomized, placebo-controlled, 90-day study of emixustat hydrochloride in geographic atrophy associated with dry age-related macular degeneration Histologic basis of variations in retinal pigment epithelium autofluorescence in eyes with geographic atrophy.Multifunctional PEG retinylamine conjugate provides prolonged protection against retinal degeneration in mice.Clinical characteristics and current treatment of age-related macular degeneration.Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles.Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization.Molecular pharmacodynamics of emixustat in protection against retinal degeneration.Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front.Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium.A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation The retina rapidly incorporates ingested C20-D₃-vitamin A in a swine model.Retinoids and Retinal Diseases.Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina.Inner and outer retinal changes in retinal degenerations associated with ABCA4 mutations.Advances in the management of macular degeneration.Complement pathway biomarkers and age-related macular degeneration.Recent developments in age-related macular degeneration: a review.Current drug and molecular therapies for the treatment of atrophic age-related macular degeneration: phase I to phase III clinical development.Vitamin A and Vision.Bioanalysis of emixustat (ACU-4429) in whole blood collected with volumetric absorptive microsampling by LC-MS/MS.A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration.Direct Treatment Costs of Neovascular Age-related Macular Degeneration and Comparison of Gained and/or Preserved Vision with Expenditure.New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models.A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.

P2860

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P2860

Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator.

http://www.wikidata.org/entity/Q34180463

description

2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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name

Safety and effect on rod funct ...... lecule visual cycle modulator.

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Safety and effect on rod funct ...... lecule visual cycle modulator.

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Safety and effect on rod funct ...... lecule visual cycle modulator.

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Safety and effect on rod funct ...... lecule visual cycle modulator.

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Safety and effect on rod funct ...... lecule visual cycle modulator.

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Safety and effect on rod funct ...... lecule visual cycle modulator.

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Safety and effect on rod funct ...... lecule visual cycle modulator.

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Safety and effect on rod funct ...... lecule visual cycle modulator.

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Nancy L Boman

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Robert David

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Ryo Kubota

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Shiva Patil

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Suresh Mallikaarjun

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scholarly article

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