Mutations in the SAM domain of the ETV6-NTRK3 chimeric tyrosine kinase block polymerization and transformation activity.
about
SAM domain-based protein oligomerization observed by live-cell fluorescence fluctuation spectroscopyABL tyrosine kinases: evolution of function, regulation, and specificitySAM domain-dependent activity of PfTKL3, an essential tyrosine kinase-like kinase of the human malaria parasite Plasmodium falciparumThe many faces of SAMThe ETV6-NTRK3 chimeric tyrosine kinase suppresses TGF-beta signaling by inactivating the TGF-beta type II receptorHuman cataract mutations in EPHA2 SAM domain alter receptor stability and function.Expression of ETV6-NTRK in classical, cellular and mixed subtypes of congenital mesoblastic nephroma.Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies.Sterile alpha motif domain-mediated self-association plays an essential role in modulating the activity of the Drosophila ETS family transcriptional repressor Yan.Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation.Genomic profiling of breast secretory carcinomas reveals distinct genetics from other breast cancers and similarity to mammary analog secretory carcinomas.Characterization of a newly identified ETV6-NTRK3 fusion transcript in acute myeloid leukemia.NTRK3 kinase fusions in Spitz tumoursThe insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.DNA Occupancy of Polymerizing Transcription Factors: A Chemical Model of the ETS Family Factor Yan.A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.
P2860
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P2860
Mutations in the SAM domain of the ETV6-NTRK3 chimeric tyrosine kinase block polymerization and transformation activity.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Mutations in the SAM domain of ...... n and transformation activity.
@ast
Mutations in the SAM domain of ...... n and transformation activity.
@en
Mutations in the SAM domain of ...... n and transformation activity.
@nl
type
label
Mutations in the SAM domain of ...... n and transformation activity.
@ast
Mutations in the SAM domain of ...... n and transformation activity.
@en
Mutations in the SAM domain of ...... n and transformation activity.
@nl
prefLabel
Mutations in the SAM domain of ...... n and transformation activity.
@ast
Mutations in the SAM domain of ...... n and transformation activity.
@en
Mutations in the SAM domain of ...... n and transformation activity.
@nl
P2093
P2860
P1476
Mutations in the SAM domain of ...... n and transformation activity.
@en
P2093
Aruna M Somasiri
Cristina E Tognon
Lawrence P McIntosh
Poul H B Sorensen
P2860
P304
P356
10.1128/MCB.24.11.4636-4650.2004
P407
P577
2004-06-01T00:00:00Z