Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties.
about
The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculatureDesign, synthesis and biological evaluation of ligands selective for the melanocortin-3 receptorInteractions of human melanocortin 4 receptor with nonpeptide and peptide agonistsThe Melanocortin Receptor System: A Target for Multiple Degenerative DiseasesNew melanocortin 1 receptor binding motif based on the C-terminal sequence of alpha-melanocyte-stimulating hormone.Effects of melanocortin 1 receptor agonists in experimental nephropathies.Selected melanocortin 1 receptor single-nucleotide polymorphisms differentially alter multiple signaling pathwaysOpioid and melanocortin receptors: do they have overlapping pharmacophores?Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors.Modified melanocortin tetrapeptide Ac-His-dPhe-Arg-Trp-NH at the arginine side chain with ureas and thioureas.Melanocortin receptor subtypes are expressed on cells in the oligodendroglial lineage and signal ACTH protection.Melanocortin 1 receptor agonist protects podocytes through catalase and RhoA activation.The melanoma-linked "redhead" MC1R influences dopaminergic neuron survival.
P2860
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P2860
Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@ast
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@en
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@nl
type
label
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@ast
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@en
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@nl
prefLabel
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@ast
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@en
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@nl
P2093
P356
P1476
Discovery of tyrosine-based po ...... anti-inflammatory properties.
@en
P2093
Ashish Khanna
George C Morton
Huji Tuerdi
John E Macor
John S Tokarski
Kenneth E Carlson
R Michael Lawrence
Timothy F Herpin
P304
P356
10.1021/JM025600I
P407
P577
2003-03-01T00:00:00Z