Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix.
about
Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examplescis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospectsX-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adductThe Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) ProdrugsStudy of the interaction of DNA with cisplatin and other Pd(II) and Pt(II) complexes by atomic force microscopy.The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.Binding of cis- and trans-dichlorodiammineplatinum(II) to the nucleosome coreNanocarriers for delivery of platinum anticancer drugs.Electron microscopic measurement of chain flexibility of poly(dG-dC).poly(dG-dC) modified by cis-diamminedichloroplatinum(II).Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.Lesion selectivity in blockage of lambda exonuclease by DNA damage.Differences in unwinding of supercoiled DNA induced by the two enantiomers of anti-benzo[a]pyrene diol epoxide.Unwinding of supercoiled DNA by cis- and trans-diamminedichloroplatinum(II): influence of the torsional strain on DNA unwinding.Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro.DNA alkylation and unwinding induced by benzo[a]pyrene diol epoxide: modulation by ionic strength and superhelicity.Base-pair substitution hotspots in GAG and GCG nucleotide sequences in Escherichia coli K-12 induced by cis-diamminedichloroplatinum (II).Understanding the effect of carbonate ion on cisplatin binding to DNACisplatin damage overrides the predefined rotational setting of positioned nucleosomes.Functional mechanotransduction is required for cisplatin-induced hair cell death in the zebrafish lateral line.cis-diamminedichloroplatinum(II) induced distortion of a single and double stranded deoxydecanucleosidenonaphosphate studied by nuclear magnetic resonance.Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies.Photoswitching the cytotoxic properties of platinum(II) compounds.A site-selective, irreversible inhibitor of the DNA replication auxiliary factor proliferating cell nuclear antigen (PCNA).The induction of lysis in lysogenic strains of Escherichia coli by a new antitumor transplatin derivative and its DNA interactions.Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups.Molecular imaging of p53 signal pathway in lung cancer cell cycle arrest induced by cisplatin.Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies.Influence of chromosome integrity on Escherichia coli cell division.Structural alterations of pathologically or physiologically modified DNA.Binding of [(dien)PtCl] Cl to poly(dG-dC)-poly(dG-dC) facilitates the B goes to Z conformational transitionReactions of the UVRABC excision nuclease with DNA damaged by diamminedichloroplatinum(II).Binding of meso-tetra (4-N-methylpyridyl) porphine to DNA.Interaction of cis-diamminedichloroplatinum(II) with phi X174 DNA.Determination of binding mode: intercalation.Combining imaging and anticancer properties with new heterobimetallic Pt(ii)/M(i) (M = Re, 99mTc) complexes.Mechanism of tracking and cleavage of adduct-damaged DNA substrates by the mammalian 5'- to 3'-exonuclease/endonuclease RAD2 homologue 1 or flap endonuclease 1.A light-activated metal complex targets both DNA and RNA in a fluorescent in vitro transcription and translation assay.Effect of cis-diamminedichloroplatinum (II) on rat thymocyte membrane potential.Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage.Study of the synthesis, antiproliferative properties, and interaction with DNA and polynucleotides of cisplatin-like Pt(II) complexes containing carcinogenic polyaromatic amines.
P2860
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P2860
Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix.
description
1979 nî lūn-bûn
@nan
1979 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1979 թվականի մարտին հրատարակված գիտական հոդված
@hy
1979年の論文
@ja
1979年論文
@yue
1979年論文
@zh-hant
1979年論文
@zh-hk
1979年論文
@zh-mo
1979年論文
@zh-tw
1979年论文
@wuu
name
Binding of cis- and trans-dichlorodiammineplatinum
@nl
Binding of cis- and trans-dich ...... hortening of the double helix.
@ast
Binding of cis- and trans-dich ...... hortening of the double helix.
@en
type
label
Binding of cis- and trans-dichlorodiammineplatinum
@nl
Binding of cis- and trans-dich ...... hortening of the double helix.
@ast
Binding of cis- and trans-dich ...... hortening of the double helix.
@en
prefLabel
Binding of cis- and trans-dichlorodiammineplatinum
@nl
Binding of cis- and trans-dich ...... hortening of the double helix.
@ast
Binding of cis- and trans-dich ...... hortening of the double helix.
@en
P2093
P356
P1433
P1476
Binding of cis- and trans-dich ...... hortening of the double helix.
@en
P2093
P304
P356
10.1126/SCIENCE.370979
P407
P577
1979-03-01T00:00:00Z