The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.
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Interactions of the human MCM-BP protein with MCM complex components and Dbf4Structural Mechanisms of Hexameric Helicase Loading, Assembly, and UnwindingMechanisms for initiating cellular DNA replicationThe Mcm2-7 replicative helicase: a promising chemotherapeutic targetA dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesisAnalysis of the Costructure of the Simian Virus 40 T-Antigen Origin Binding Domain with Site I Reveals a Correlation between GAGGC Spacing and Spiral AssemblyA Role for USP7 in DNA ReplicationThe replication initiation protein Sld2 regulates helicase assembly.Mechanisms Governing DDK Regulation of the Initiation of DNA ReplicationRegulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome StabilityAn Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication InitiationThe Dbf4-Cdc7 kinase promotes Mcm2-7 ring opening to allow for single-stranded DNA extrusion and helicase assembly.ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryoteStructural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionEukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication.Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damageA unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNAGeminin inhibits a late step in the formation of human pre-replicative complexes.Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zoneDpb11 protein helps control assembly of the Cdc45·Mcm2-7·GINS replication fork helicase.Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase.Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis.Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication.A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/MOrigin DNA Melting-An Essential Process with Divergent Mechanisms.The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.The eukaryotic CMG helicase pumpjack and integration into the replisome.Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase.Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.DNA replication and homologous recombination factors: acting together to maintain genome stability.From structure to mechanism-understanding initiation of DNA replication.Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate.Multiple functions for Mcm2-7 ATPase motifs during replication initiationBiochemistry: Molecular hurdles cleared with ease.
P2860
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P2860
The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.
description
2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@ast
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@en
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@nl
type
label
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@ast
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@en
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@nl
prefLabel
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@ast
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@en
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'.
@nl
P2860
P356
P1476
The Saccharomyces cerevisiae M ...... of the putative Mcm2-7 'gate'
@en
P2093
Anthony Schwacha
P2860
P304
P356
10.1093/NAR/GKQ422
P407
P577
2010-05-19T00:00:00Z