RRM1-induced metastasis suppression through PTEN-regulated pathways. - Wikidata - wikimedia - TriplyDB

RRM1-induced metastasis suppression through PTEN-regulated pathways.

RRM1-induced metastasis suppression through PTEN-regulated pathways.

http://www.wikidata.org/entity/Q34189695

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Nicotine promotes tumor growth and metastasis in mouse models of lung cancer Overexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesis Altered gene expression in human cells treated with the insecticide diazinon: correlation with decreased DNA excision repair capacity XPC mRNA level may predict relapse in never-smokers with non-small cell lung cancers Ubiquitination and degradation of ribonucleotide reductase M1 by the polycomb group proteins RNF2 and Bmi1 and cellular response to gemcitabine MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer Long-term in-vivo tumorigenic assessment of human culture-expanded adipose stromal/stem cells Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development Metabolic genes in cancer: their roles in tumor progression and clinical implications RRM1 single nucleotide polymorphism -37C-->A correlates with progression-free survival in NSCLC patients after gemcitabine-based chemotherapy.Nucleotide metabolism, oncogene-induced senescence and cancer.Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes RIN1 is a breast tumor suppressor gene.Concurrent analysis of human equilibrative nucleoside transporter 1 and ribonucleotide reductase subunit 1 expression increases predictive value for prognosis in cholangiocarcinoma patients treated with adjuvant gemcitabine-based chemotherapy A phase II trial of triapine (NSC# 663249) and gemcitabine as second line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503 A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy.RRM1 gene expression in peripheral blood is predictive of shorter survival in Chinese patients with advanced non-small-cell lung cancer treated by gemcitabine and platinum ERCC1 and RRM1 in the international adjuvant lung trial by automated quantitative in situ analysis.Microenvironmental Influences on Metastasis Suppressor Expression and Function during a Metastatic Cell's Journey.Nicotinic acetylcholine receptor signaling in tumor growth and metastasis Ribonucleotide reductase large subunit M1 predicts poor survival due to modulation of proliferative and invasive ability of gastric cancer.Investigation of Pokemon-regulated proteins in hepatocellular carcinoma using mass spectrometry-based multiplex quantitative proteomics.How close are we to customizing chemotherapy in early non-small cell lung cancer?Modulation of the ribonucleotide reductase M1-gemcitabine interaction in vivo by N-ethylmaleimide.Pharmacogenomics: a reality or still a promise?Molecular Markers with Predictive and Prognostic Relevance in Lung Cancer Progress in personalizing chemotherapy for bladder cancer Current progress of siRNA/shRNA therapeutics in clinical trials.Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer.Pharmacogenomics in lung cancer: an analysis of DNA repair gene expression in patients treated with platinum-based chemotherapy.Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy.Expression of PTEN and KAI1 tumor suppressor genes in pancreatic carcinoma and its association with different pathological factors.Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms.Molecular predictors of chemotherapy response in non-small-cell lung cancer.Focal adhesion kinase: a promising target for anticancer therapy.RRM1 *151A>T, RRM1 -756T>C, and RRM1 -585T>Gis associated with increased susceptibility of lung cancer in Chinese patients.Ribonucleotide reductase subunit M1 expression in resectable, muscle-invasive urothelial cancer correlates with survival in younger patients The prognostic value of ERCC1 and RRM1 gene expression in completely resected non-small cell lung cancer: tumor recurrence and overall survival Gemcitabine and carboplatin demonstrate synergistic cytotoxicity in cervical cancer cells by inhibiting DNA synthesis and increasing cell apoptosis.Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer.

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RRM1-induced metastasis suppression through PTEN-regulated pathways.

http://www.wikidata.org/entity/Q34189695

description

2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

RRM1-induced metastasis suppression through PTEN-regulated pathways.

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RRM1-induced metastasis suppression through PTEN-regulated pathways.

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RRM1-induced metastasis suppression through PTEN-regulated pathways.

@nl

type

label

RRM1-induced metastasis suppression through PTEN-regulated pathways.

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RRM1-induced metastasis suppression through PTEN-regulated pathways.

@en

RRM1-induced metastasis suppression through PTEN-regulated pathways.

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prefLabel

RRM1-induced metastasis suppression through PTEN-regulated pathways.

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RRM1-induced metastasis suppression through PTEN-regulated pathways.

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RRM1-induced metastasis suppression through PTEN-regulated pathways.

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RRM1-induced metastasis suppression through PTEN-regulated pathways.

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Ashish Gautam

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Gerold Bepler

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Zhan-Rong Li

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P2860

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

Rho GTPases: signaling, migration, and invasion.

Three tumor-suppressor regions on chromosome 11p identified by high-resolution deletion mapping in human non-small-cell lung cancer

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

The R1 component of mammalian ribonucleotide reductase has malignancy-suppressing activity as demonstrated by gene transfer experiments.

Defining a novel cis-element in the 3'-untranslated region of mammalian ribonucleotide reductase component R2 mRNA. cis-trans-interactions and message stability.

Profiling the downstream genes of tumor suppressor PTEN in lung cancer cells by complementary DNA microarray.

Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhances their invasive potential.

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10.1038/SJ.ONC.1206232

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