Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol.
about
Isolation and characterization of human apolipoprotein M-containing lipoproteinsApolipoprotein A-I and CancerProteomics investigations of HDL: challenges and promiseHDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disordersApolipoprotein A-I, cyclodextrins and liposomes as potential drugs for the reversal of atherosclerosis. A review.Apolipoprotein A-I, phospholipid vesicles, and cyclodextrins as potential anti-atherosclerotic drugs: delivery, pharmacokinetics, and efficacy.Novel approaches to treating cardiovascular disease: lessons from Tangier disease.Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneysSetting the course for apoAII: a port in sight?Structure/function relationships of apolipoprotein a-I mimetic peptides: implications for antiatherogenic activities of high-density lipoprotein.Anti-inflammatory and cholesterol-reducing properties of apolipoprotein mimetics: a reviewOral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice.Apolipoprotein mimetic peptides: Mechanisms of action as anti-atherogenic agents.An amphipathic helical region of the N-terminal barrel of phospholipid transfer protein is critical for ABCA1-dependent cholesterol efflux.Mechanism underlying apolipoprotein E (ApoE) isoform-dependent lipid efflux from neural cells in culture.Biological properties of apolipoprotein a-I mimetic peptides.ABCA1: regulation, trafficking and association with heteromeric proteins.An amphipathic alpha-helical peptide from apolipoprotein A1 stabilizes protein polymer vesicles.Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathwayRegulation of ABCA1 functions by signaling pathwaysHelix stabilization of amphipathic peptides by hydrocarbon stapling increases cholesterol efflux by the ABCA1 transporter.Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier DiseaseSite-specific oxidation of apolipoprotein A-I impairs cholesterol export by ABCA1, a key cardioprotective function of HDL.ApoA-1 mimetic restores adiponectin expression and insulin sensitivity independent of changes in body weight in female obese mice.Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages.Asymmetry in the lipid affinity of bihelical amphipathic peptides. A structural determinant for the specificity of ABCA1-dependent cholesterol efflux by peptides.Multiple indications for anti-inflammatory apolipoprotein mimetic peptides.Apolipoprotein A-I mimetic peptide helix number and helix linker influence potentially anti-atherogenic properties.The macrophage cholesterol exporter ABCA1 functions as an anti-inflammatory receptor.The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.Modulation of adipose tissue lipolysis and body weight by high-density lipoproteins in mice.Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis.Vasculoprotective Effects of Apolipoprotein Mimetic Peptides: An Evolving Paradigm In Hdl Therapy (Vascular Disease Prevention, In Press.).Recombinant high-density lipoprotein formulations.High-density lipoprotein mimetics: promises and challenges.Comparison of anti-endotoxin activity of apoE and apoA mimetic derivatives of a model amphipathic peptide 18A.Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C delta pathway.Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1- or ABCA7-dependent manner.Janus kinase 2 modulates the lipid-removing but not protein-stabilizing interactions of amphipathic helices with ABCA1.Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway.
P2860
Q24336276-894E156F-2A54-4A36-9C14-B6B1F3864002Q26776188-9DCFD698-2324-4A3F-8126-0B258AFB09E0Q27000995-92BBF183-C435-4E7C-9E4F-3CC83ABFB7AAQ27691344-591DA856-C93E-4905-8CD4-F1DC8935B928Q30327074-10731EAC-D319-4D9B-A105-A960A312202DQ30327228-35A62C30-92C7-4ACE-A3F6-F6098A48DF45Q32066326-AD3A5671-C04D-4324-BC65-AC5F9DAD37D0Q33901965-241AA095-55A3-4324-ABD9-34BB68D3D794Q33939998-03DC403D-CDC3-4F61-843B-4D64DA29B122Q34144449-8D0FE0D3-A171-454A-B8F2-2258007A857CQ34238630-D9434F4F-31DE-4534-80C7-C3AC111ED536Q34287846-ACDCFCAA-2F5D-4D7D-8024-CA81CF132685Q34594140-289A0E50-7BF7-4FD0-AD99-C9E15A33C8A4Q34655812-BC91D0C0-8593-474B-AE3B-F0B5D4DCB286Q34730744-2035A301-7BA9-4D8A-9C15-81B3C2ED0EC3Q34927488-0BF89C16-2907-46A8-8C2E-30267CD98D17Q35009337-009F6011-F3C3-4B2D-90C0-0C93BCC142ABQ35082742-F947A6A2-E5A2-4D8D-BA96-B69D05A245B7Q35166941-7D8F41FE-6B49-499A-996C-D13F3D75B275Q35626943-C65EEB93-F3C1-48F3-94FC-3926816E5B35Q35660283-1E92BFA2-F5DF-466D-ABA0-83F75AE25583Q35749982-F9A3515A-7743-4ACE-A64B-522A8A04A896Q35783321-E269E41F-9C68-4804-9DD5-B728877F84A6Q35926657-751039EF-CB0D-463F-BA3C-98F2C32391B3Q36843317-D8FDC895-BC69-4A96-9D37-D8CD748EDF29Q36973725-BBF0C873-568B-4737-BCE7-9D4D31C7CB1AQ37308178-9A1518C4-B34A-4E49-AF60-6B29AED72CC0Q37334578-C01C062F-8BD1-4BA4-B520-0307982514D9Q37431941-DD1400B2-34AA-421D-B884-825428007D52Q37512515-55EF43A8-F55C-4CF6-8A5D-378BEC75796AQ37614469-3767D832-9F3D-4BE7-B3C9-629316A6B8AAQ37671683-FF254B27-7D4A-4F95-B6B5-366F30EBF12DQ37677573-C10E6DAB-C788-4478-BE4A-414A6914638BQ37807911-78656AA0-EB16-4F0E-A9BB-E861DD5E5023Q38650575-FF90FC41-7FB1-4FA3-831C-99279A2D2178Q39045016-13A146EE-194E-4393-B52D-5BFB7B470687Q40166045-E5DCFA27-AF26-4A30-AE47-CE6B9162BD37Q40293994-BD2BC639-2670-47FA-B3A6-5566307A453CQ40364626-E14E409F-FB2F-454E-8584-D36E9DFE2548Q40381992-E675A9D7-E701-4D0C-B33D-EB37C0DF89F4
P2860
Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol.
description
1994 nî lūn-bûn
@nan
1994 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@ast
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@en
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@nl
type
label
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@ast
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@en
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@nl
prefLabel
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@ast
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@en
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@nl
P2093
P2860
P356
P1476
Synthetic amphipathic helical ...... clearing cellular cholesterol.
@en
P2093
A J Mendez
G M Anantharamaiah
J P Segrest
P2860
P304
P356
10.1172/JCI117515
P407
P577
1994-10-01T00:00:00Z