Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury
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Regulation of Microtubule Dynamics in Axon Regeneration: Insights from C. elegansThe PHR proteins: intracellular signaling hubs in neuronal development and axon degenerationNeurodegeneration and microtubule dynamics: death by a thousand cutsThe DLK signalling pathway--a double-edged sword in neural development and regenerationMicrofluidic chips for in vivo imaging of cellular responses to neural injury in Drosophila larvaeThe Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and β-CateninThe Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat proteinDynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity.RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal developmentZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonatesMislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria.Inhibiting poly(ADP-ribosylation) improves axon regenerationDevelopmental Function of the PHR Protein RPM-1 Is Required for Learning in Caenorhabditis elegans.Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways.Axon injury and stress trigger a microtubule-based neuroprotective pathway.Kinesin-1-powered microtubule sliding initiates axonal regeneration in Drosophila cultured neurons.Spastin, atlastin, and ER relocalization are involved in axon but not dendrite regeneration.A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degenerationSkpA restrains synaptic terminal growth during development and promotes axonal degeneration following injuryDLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injuryUsing microfluidics chips for live imaging and study of injury responses in Drosophila larvae.Axon regeneration mechanisms: insights from C. elegansAxon regeneration pathways identified by systematic genetic screening in C. elegans.Axon injury and regeneration in the adult DrosophilaPreserve and protect: maintaining axons within functional circuits.RHGF-1/PDZ-RhoGEF and retrograde DLK-1 signaling drive neuronal remodeling on microtubule disassemblyThe microtubule minus-end-binding protein patronin/PTRN-1 is required for axon regeneration in C. elegansAn injury paradigm to investigate central nervous system repair in DrosophilaIdentification of a peptide inhibitor of the RPM-1 · FSN-1 ubiquitin ligase complexBimodal control of dendritic and axonal growth by the dual leucine zipper kinase pathway.Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration.DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activityDrosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.MAP kinase cascades regulating axon regeneration in C. elegansExtrinsic and intrinsic determinants of nerve regenerationRegulation of axon regeneration by the RNA repair and splicing pathway.FoxO limits microtubule stability and is itself negatively regulated by microtubule disruptionA conditioning lesion protects axons from degeneration via the Wallenda/DLK MAP kinase signaling cascadeSARM1 activation triggers axon degeneration locally via NAD⁺ destruction
P2860
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P2860
Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Protein turnover of the Wallen ...... rade response to axonal injury
@ast
Protein turnover of the Wallen ...... rade response to axonal injury
@en
Protein turnover of the Wallen ...... rade response to axonal injury
@nl
type
label
Protein turnover of the Wallen ...... rade response to axonal injury
@ast
Protein turnover of the Wallen ...... rade response to axonal injury
@en
Protein turnover of the Wallen ...... rade response to axonal injury
@nl
prefLabel
Protein turnover of the Wallen ...... rade response to axonal injury
@ast
Protein turnover of the Wallen ...... rade response to axonal injury
@en
Protein turnover of the Wallen ...... rade response to axonal injury
@nl
P2093
P2860
P356
P1476
Protein turnover of the Wallen ...... rade response to axonal injury
@en
P2093
Pavan Bhat
Ronny Ewanek
P2860
P304
P356
10.1083/JCB.201006039
P407
P577
2010-10-01T00:00:00Z