Synthetic lethality of cohesins with PARPs and replication fork mediators. - Wikidata - wikimedia - TriplyDB

Synthetic lethality of cohesins with PARPs and replication fork mediators.

Synthetic lethality of cohesins with PARPs and replication fork mediators.

http://www.wikidata.org/entity/Q34192912

about

Synthetic lethality and cancer: cohesin and PARP at the replication fork An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development Role of SMC1 in overcoming drug resistance in triple negative breast cancer Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy.Drugging the Cancers Addicted to DNA Repair.Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin The LSH/HELLS homolog Irc5 contributes to cohesin association with chromatin in yeast The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 Complex Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.Targeted therapies for advanced Ewing sarcoma family of tumors.PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors.Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork.Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation.Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer PARP1 Differentially Interacts with Promoter region of DUX4 Gene in FSHD Myoblasts Contemporary, yeast-based approaches to understanding human genetic variation.Cohesin association to replication sites depends on rad50 and promotes fork restart Synthetic lethality and cancer.Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1.55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability. Whistler, British Columbia, Canada, 14–18 March 2012.

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Synthetic lethality of cohesins with PARPs and replication fork mediators.

http://www.wikidata.org/entity/Q34192912

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Synthetic lethality of cohesins with PARPs and replication fork mediators.

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Synthetic lethality of cohesins with PARPs and replication fork mediators.

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Synthetic lethality of cohesins with PARPs and replication fork mediators.

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type

label

Synthetic lethality of cohesins with PARPs and replication fork mediators.

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Synthetic lethality of cohesins with PARPs and replication fork mediators.

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Synthetic lethality of cohesins with PARPs and replication fork mediators.

@nl

prefLabel

Synthetic lethality of cohesins with PARPs and replication fork mediators.

@ast

Synthetic lethality of cohesins with PARPs and replication fork mediators.

@en

Synthetic lethality of cohesins with PARPs and replication fork mediators.

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JOURNAL.PGEN.1002574

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Synthetic lethality of cohesins with PARPs and replication fork mediators.

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Ann M Rose

http://www.w3.org/2001/XMLSchema#string

Derek M van Pel

http://www.w3.org/2001/XMLSchema#string

Elizabeth Ferree

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Irene Barrett

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Jessica L McLellan

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Kevin Ushey

http://www.w3.org/2001/XMLSchema#string

Payal Sipahimalani

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Philip Hieter

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P2860

The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components

Cohesin acetylation speeds the replication fork

Wapl controls the dynamic association of cohesin with chromatin

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

Identification of protein complexes required for efficient sister chromatid cohesion.

Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion.

Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae.

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