Activation of metabotropic glutamate receptor mGlu5 on nuclear membranes mediates intranuclear Ca2+ changes in heterologous cell types and neurons.
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The human gonadotropin releasing hormone type I receptor is a functional intracellular GPCR expressed on the nuclear membranePositive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortexEndoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expressionNuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signalingAgonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptorsModulation of α(2C) adrenergic receptor temperature-sensitive trafficking by HSP90Developmental and adult expression patterns of the G-protein-coupled receptor GPR88 in the rat: Establishment of a dual nuclear-cytoplasmic localizationDysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismPharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth.Calcium signaling in synapse-to-nucleus communicationNuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cellsLocation-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cellsRegulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP-3Functional G protein-coupled receptors on nuclei from brain and primary cultured neuronsActivation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein.Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and colocalization with the metabotropic glutamate receptor 5 in the striatum.Intracellular mGluR5 plays a critical role in neuropathic painNuclear Na+/K+-ATPase plays an active role in nucleoplasmic Ca2+ homeostasis.The proto-oncogene SET interacts with muscarinic receptors and attenuates receptor signaling.Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca²⁺ in adult cardiac myocytes.The insulin receptor translocates to the nucleus to regulate cell proliferation in liver.Proteomic analysis of native metabotropic glutamate receptor 5 protein complexes reveals novel molecular constituentsCardiac alpha1-adrenergic receptors: novel aspects of expression, signaling mechanisms, physiologic function, and clinical importanceIntracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterpartsMechanisms Associated with Activation of Intracellular Metabotropic Glutamate Receptor, mGluR5.Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus.G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function.Role of the nuclear envelope in calcium signalling.Nuclear phosphoinositides and their impact on nuclear functions.Neuronal activity-regulated gene transcription: how are distant synaptic signals conveyed to the nucleus?Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release.Regulation of phosphatidylinositol-specific phospholipase C at the nuclear envelope in cardiac myocytes.Sequences within the C Terminus of the Metabotropic Glutamate Receptor 5 (mGluR5) Are Responsible for Inner Nuclear Membrane Localization.Intracellular distribution of functional M(1) -muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells.The heterotrimeric [corrected] G protein subunit G alpha i is present on mitochondria.Nuclear localization of functional metabotropic glutamate receptor mGlu1 in HEK293 cells and cortical neurons: role in nuclear calcium mobilization and development.Cloning and characterization of a family C orphan G-protein coupled receptor.Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression.
P2860
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P2860
Activation of metabotropic glutamate receptor mGlu5 on nuclear membranes mediates intranuclear Ca2+ changes in heterologous cell types and neurons.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Activation of metabotropic glu ...... logous cell types and neurons.
@ast
Activation of metabotropic glu ...... logous cell types and neurons.
@en
Activation of metabotropic glu ...... logous cell types and neurons.
@nl
type
label
Activation of metabotropic glu ...... logous cell types and neurons.
@ast
Activation of metabotropic glu ...... logous cell types and neurons.
@en
Activation of metabotropic glu ...... logous cell types and neurons.
@nl
prefLabel
Activation of metabotropic glu ...... logous cell types and neurons.
@ast
Activation of metabotropic glu ...... logous cell types and neurons.
@en
Activation of metabotropic glu ...... logous cell types and neurons.
@nl
P2093
P356
P1476
Activation of metabotropic glu ...... logous cell types and neurons.
@en
P2093
Andreas Burkhalter
Carmelo Romano
Karen L O'Malley
Yuh-Jiin I Jong
Yuri Gonchar
P304
28210-28219
P356
10.1074/JBC.M300792200
P407
P577
2003-05-07T00:00:00Z