Altered telomeres in tumors with ATRX and DAXX mutations. - Wikidata - wikimedia - TriplyDB

Altered telomeres in tumors with ATRX and DAXX mutations.

Altered telomeres in tumors with ATRX and DAXX mutations.

http://www.wikidata.org/entity/Q34196696

about

Cancer genome landscapes ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression ATRX dysfunction induces replication defects in primary mouse cells Recent progress in pancreatic cancer Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies Surgical and molecular pathology of pancreatic neoplasms New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment Telomere biology: Rationale for diagnostics and therapeutics in cancer Linking epithelial-to-mesenchymal-transition and epigenetic modifications Histone regulation in the CNS: basic principles of epigenetic plasticity Telomere regulation in pluripotent stem cells Alternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progression Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumors Histone H3 mutations--a special role for H3.3 in tumorigenesis?Genetic basis of pancreas cancer development and progression: insights from whole-exome and whole-genome sequencing Modern brain tumor imaging Every amino acid matters: essential contributions of histone variants to mammalian development and disease RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis.A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype Telomere maintenance and the etiology of adult glioma Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells Histone H3.3 maintains genome integrity during mammalian development Molecular Markers in Low-Grade Glioma-Toward Tumor Reclassification Decreased expression of the chromatin remodeler ATRX associates with melanoma progression Epidemiologic and molecular prognostic review of glioblastoma Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition.Histone variants and epigenetics.Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site.Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands.

P2860

Q22242276-1A6921EC-C4BA-41C0-B799-CA0AE3B4C154 Q24306749-C81606BE-E4F6-4085-A68C-F52C19F1DD3B Q24339453-DE049DDE-9B9E-4CBC-B8D3-65B3E606E948 Q24626346-B4DB3318-41DE-40B8-94CE-A4D233CE0709 Q26744271-E8033632-D6F2-4F21-ADF9-289E915CC7D8 Q26748615-8DB86565-5C27-41D9-AF7B-0F58F406EEE8 Q26771668-0420A551-3F39-448B-A97E-6CE7AD00D79B Q26785952-67070898-A93E-4DE6-B32B-3E20C1BD9CF2 Q26796323-10D4CDF6-CDA3-4CF7-8AC6-2388E2C74730 Q26824575-C3D4AD0C-D689-4A63-B155-1CA0EC112353 Q26829142-257330A3-E6E3-4707-A77D-F4587E5C1EE6 Q26851428-A24EAD8F-220F-43D8-BE03-32FC4D914E00 Q26862886-BD6CB9B7-87B7-4A02-B258-7AA1E6386644 Q26864920-05B3956E-B1D1-4BF9-B180-2D195C12D891 Q26865965-BC1CF193-2235-4CC8-BCBE-8EF74CC9D7F3 Q26991615-243FDBC5-B9E4-4F52-9AF6-1B1AB7B34D69 Q27002344-B30C7ACD-ED63-4C19-BE68-BC92D44B23F9 Q27008522-355E3727-93F5-4308-97DB-A98F5AA12179 Q27306288-B6AC0A01-D00A-4948-AAEA-114A226122B9 Q27852494-2F580122-64DF-4FC4-9A8A-8180328F29C7 Q27936513-8807CBB4-7E72-4F41-B6CF-9B37A6D3390A Q28070584-80F98C4A-C891-48D5-9E2C-2E111007C059 Q28071562-F290290D-49DA-4349-919A-A7BDC31668DC Q28084275-BCD3F675-2842-4747-9A14-65DA4C5E02F0 Q28115086-7A3FD123-2E26-4D2E-827B-659C1950E95A Q28116488-061313B0-7FB8-4E8C-969A-A307EFD2644E Q28118722-007EBB55-E690-469C-A5FD-94E5ABE1FC7D Q28264875-74A94539-912B-4196-BF70-9633249ED98B Q28383205-C460560C-30FE-47EA-97E9-F95749FB9F71 Q28385936-8E8FAF3B-9A46-4221-9B27-E0DBF85FF235 Q28395302-4A000971-480E-426F-A251-EBDF7D8132C6 Q28535568-07E6148C-FF59-4616-A74C-99B261A10B5B Q28587544-0C658287-B1C7-4AF3-A5F6-5C6F14E98732 Q28658254-F0B6E9C2-B661-4B1D-B03B-C542BD934292 Q30301007-357C52D0-C579-4FDF-BAAA-4FDEAF85764A Q30459320-B66752DC-A86D-4436-BE6A-776EF5F2D2A2 Q30541321-CDCD9D0F-2B6E-4C78-BAED-FEBBC5377284 Q30833310-0C8E4B23-C7E2-40F4-B5E0-361C761E0C5D Q33414576-358A89B1-F1B5-4F9E-A55B-CADA09FEBDF4 Q33558285-CD9A32B1-35EB-4745-BC73-0C84DBB488F3

P2860

Altered telomeres in tumors with ATRX and DAXX mutations.

http://www.wikidata.org/entity/Q34196696

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Altered telomeres in tumors with ATRX and DAXX mutations.

@ast

Altered telomeres in tumors with ATRX and DAXX mutations.

@en

Altered telomeres in tumors with ATRX and DAXX mutations.

@nl

type

label

Altered telomeres in tumors with ATRX and DAXX mutations.

@ast

Altered telomeres in tumors with ATRX and DAXX mutations.

@en

Altered telomeres in tumors with ATRX and DAXX mutations.

@nl

prefLabel

Altered telomeres in tumors with ATRX and DAXX mutations.

@ast

Altered telomeres in tumors with ATRX and DAXX mutations.

@en

Altered telomeres in tumors with ATRX and DAXX mutations.

@nl

P1433

Q34196696-46B3B107-7737-4BA6-BEA5-3F35E7F8DA87

P1476

Q34196696-D73828F4-658C-4B8F-87A4-860C564405B4

P2093

Q34196696-09393F28-FD48-4D9D-BA17-7984CA91F3E6

Q34196696-0E5FC18C-0169-4327-BC78-7A348A2E051C

Q34196696-23347AE2-AE17-4713-A9CE-BD370F3BBC71

Q34196696-39DEA39D-2C0B-482A-97CB-1EF46C9217D8

Q34196696-69D84311-3B6D-4455-8AEE-DC029B1F9A02

Q34196696-7C54E26F-5649-43F0-BF51-538EC514CDA6

Q34196696-8F6363F4-49E3-4F13-A855-C0D7478CC25E

Q34196696-910258FE-5F2E-4BC1-8C21-102F0EC64D62

Q34196696-9AAE2B1A-37D5-49D7-A5FA-A5934C163F4A

Q34196696-AA68250C-D218-4A37-AF23-C5B56494A5F1

P2860

Q34196696-00ACBF52-6A77-4C5D-8134-E8F9B1FB1D54

Q34196696-134B0594-6816-4D4F-BF2E-86042F21556B

Q34196696-3F7A5FBD-6D26-4375-B2C0-E658004E5208

Q34196696-46BBB200-27E4-4D10-98E8-7D401DEC654B

Q34196696-4A93183A-F3A8-464B-ADBD-0352FB1A33B3

Q34196696-4C1C5365-EF77-478B-B876-4E63EC0CC703

Q34196696-4E274066-6BCE-4463-8F54-3304388B1F12

Q34196696-59F8DAB5-E996-432F-88E7-F922BD9EE6B3

Q34196696-640772D5-E748-44A4-8D94-4BC3E5B5E245

Q34196696-67EF5A1C-BC5B-4034-A8A8-A09F70C26892

P304

Q34196696-4B1BE690-14ED-4D19-9E36-C57A6E8E9073

P31

Q34196696-9E0127B2-8B69-480C-BFD3-61141A32BEE2

P356

Q34196696-8F465D36-5B02-4268-9401-FB183B139DDE

P407

Q34196696-972133C9-82B0-44E6-A4A0-DA72E2B6BA28

P433

Q34196696-5E5B18A5-94CF-457D-B2EF-9797AC521614

P478

Q34196696-779604E0-E374-4EDA-B2E6-E8889C022B86

P50

Q34196696-553FFAB5-5CFF-4B20-81D8-ED3F1447B7F2

Q34196696-71FF8CC8-18FB-41D4-A4B4-2D7681A1F1C9

Q34196696-91BC5074-F97F-4585-9937-0B4998292E46

Q34196696-A0E4EB26-DB45-4C71-8802-1BD15B045DDB

Q34196696-F1B2156C-4F5E-4D06-A924-A49D59F050DA

Q34196696-FD4A68D1-633F-49B3-BCE7-26A8D29B7A01

P577

Q34196696-A22F2C70-90E4-4BB5-BCE2-DB9A873356FF

P5875

Q34196696-AEA844D4-E9BE-4119-983A-042C0EECBC83

P698

Q34196696-65C785E4-9F9A-44BB-8104-BC1D37F76EB4

P932

Q34196696-F4FBDDCE-5AD1-43CE-8EAC-F5CA4A9CA7FD

P356

SCIENCE.1207313

P1433

P1476

Altered telomeres in tumors with ATRX and DAXX mutations.

@en

P2093

Alan K Meeker

http://www.w3.org/2001/XMLSchema#string

Alison P Klein

http://www.w3.org/2001/XMLSchema#string

Anirban Maitra

http://www.w3.org/2001/XMLSchema#string

B Ahmed Rasheed

http://www.w3.org/2001/XMLSchema#string

Barish H Edil

http://www.w3.org/2001/XMLSchema#string

Chanjuan Shi

http://www.w3.org/2001/XMLSchema#string

Chetan Bettegowda

http://www.w3.org/2001/XMLSchema#string

Christopher M Heaphy

http://www.w3.org/2001/XMLSchema#string

Fausto J Rodriguez

http://www.w3.org/2001/XMLSchema#string

G Johan Offerhaus

http://www.w3.org/2001/XMLSchema#string

P2860

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

Distinct factors control histone variant H3.3 localization at specific genomic regions

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically

Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining

Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells

Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers.

P304

425

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1126/SCIENCE.1207313

http://www.w3.org/2001/XMLSchema#string

P407

P433

6041

http://www.w3.org/2001/XMLSchema#string

P478

333

http://www.w3.org/2001/XMLSchema#string

P50

Ralph H. Hruban

Kenneth W Kinzler

Darell D. Bigner

Bert Vogelstein

Roger E McLendon

Charles G Eberhart

P577

2011-06-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51458132

http://www.w3.org/2001/XMLSchema#string

P698

21719641

http://www.w3.org/2001/XMLSchema#string

P932

3174141

http://www.w3.org/2001/XMLSchema#string