Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein - Wikidata - wikimedia - TriplyDB

Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein

Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein

http://www.wikidata.org/entity/Q34197130

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Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia Genome-wide analysis of DNA methylation during antagonism of DMOG to MnCl2-induced cytotoxicity in the mouse substantia nigra.Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes.Shadows of an absent partner: ATP hydrolysis and phosphoenzyme turnover of the Spf1 (sensitivity to Pichia farinosa killer toxin) P5-ATPase."Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"Manganese homeostasis in the nervous system A lipid switch unlocks Parkinson's disease-associated ATP13A2 Parkinson's disease-associated human P5B-ATPase ATP13A2 increases spermidine uptake Zn²⁺ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation ATP13A2 and Alpha-synuclein: a Metal Taste in Autophagy PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity ATP13A2/PARK9 regulates secretion of exosomes and α-synuclein ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons Manganese exposure induces α-synuclein aggregation in the frontal cortex of non-human primates Exposure, epidemiology, and mechanism of the environmental toxicant manganese.Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction Genetic factors and manganese-induced neurotoxicity.Mutations in the ATP13A2 gene and Parkinsonism: a preliminary review.The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast.Common pathogenic effects of missense mutations in the P-type ATPase ATP13A2 (PARK9) associated with early-onset parkinsonism A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity.ATP13A2/PARK9 Deficiency Neither Cause Lysosomal Impairment Nor Alter α-Synuclein Metabolism in SH-SY5Y Cells.Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants.RNASeq in C. elegans Following Manganese Exposure.On the complexity of clinical and molecular bases of neurodegeneration with brain iron accumulation.The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories.Golgi phosphoprotein 4 (GPP130) is a sensitive and selective cellular target of manganese exposure.The role of ATP13A2 in Parkinson's disease: Clinical phenotypes and molecular mechanisms.A current review for biological monitoring of manganese with exposure, susceptibility, and response biomarkers.A familial ATP13A2 mutation enhances alpha-synuclein aggregation and promotes cell death.Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter.Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism.Influence of iron metabolism on manganese transport and toxicity.

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Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein

http://www.wikidata.org/entity/Q34197130

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年论文

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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Journal of Biological Chemistry

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Regulation of intracellular ma ...... ome-associated ATP13A2 protein

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P2093

Danling Wang

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Dongshen Hu

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Jieqiong Tan

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Jingwei Chi

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Li Jiang

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Qian Pan

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Tongmei Zhang

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Zhuohua Zhang

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P2860

Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cells

Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease

Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36

Brain uptake, retention, and efflux of aluminum and manganese.

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

Activity of the yeast MNN1 alpha-1,3-mannosyltransferase requires a motif conserved in many other families of glycosyltransferases

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

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29654-29662

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34

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286

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2011-07-01T00:00:00Z

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21724849

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3191006

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