Acidic polyamino acids inhibit human eosinophil granule major basic protein toxicity. Evidence of a functional role for ProMBP
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Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitorHuman eosinophil major basic protein, a mediator of allergic inflammation, is expressed by alternative splicing from two promotersHuman eosinophil peroxidase induces surface alteration, killing, and lysis of Mycobacterium tuberculosis.Crystal structure of the eosinophil major basic protein at 1.8 A. An atypical lectin with a paradigm shift in specificityLocalization of disulfide bridges and free sulfhydryl groups in human eosinophil granule major basic proteinNovel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosaceaLow anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands.Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor.Human versus mouse eosinophils: "that which we call an eosinophil, by any other name would stain as red".Function of pulmonary M2 muscarinic receptors in antigen-challenged guinea pigs is restored by heparin and poly-L-glutamate.Contractile properties of synthetic cationic polypeptides in guinea-pig isolated trachea.Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis.Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in miceMechanisms of eosinophil major basic protein-induced hyperexcitability of vagal pulmonary chemosensitive neuronsInterleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness.In vivo neutralization of eosinophil-derived major basic protein inhibits antigen-induced bronchial hyperreactivity in sensitized guinea pigs.Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways.Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs.Intramolecular inhibition of human defensin HNP-1 by its propiece.Cell damage in inflammatory and infectious sites might involve a coordinated "cross-talk" among oxidants, microbial haemolysins and ampiphiles, cationic proteins, phospholipases, fatty acids, proteinases and cytokines (an overview).Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase.Airway hyperresponsiveness induced by cationic proteins in vivo: site of action.Cationic proteins induce airway hyperresponsiveness dependent on charge interactions.
P2860
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P2860
Acidic polyamino acids inhibit human eosinophil granule major basic protein toxicity. Evidence of a functional role for ProMBP
description
1991 nî lūn-bûn
@nan
1991 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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Acidic polyamino acids inhibit ...... f a functional role for ProMBP
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P2093
P2860
P356
P1476
Acidic polyamino acids inhibit ...... f a functional role for ProMBP
@en
P2093
D A Loegering
G J Gleich
J L Checkel
K J Hamann
R H Gundel
R L Barker
P2860
P304
P356
10.1172/JCI115379
P407
P577
1991-09-01T00:00:00Z