Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity
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Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.Concurrent Inflammation Augments Antimalarial Drugs-Induced Liver Injury in RatsBioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In VitroRelationships Between Pharmacovigilance, Molecular, Structural, and Pathway Data: Revealing Mechanisms for Immune-Mediated Drug-Induced Liver Injury.Trovafloxacin enhances lipopolysaccharide-stimulated production of tumor necrosis factor-α by macrophages: role of the DNA damage response.Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or NecrosisMulti-cell type human liver microtissues for hepatotoxicity testing.3,4-Dihydroxy-benzohydroxamic acid (Didox) suppresses pro-inflammatory profiles and oxidative stress in TLR4-activated RAW264.7 murine macrophages.Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI.Organotypic liver culture models: meeting current challenges in toxicity testing.In vitro models for liver toxicity testing.Metabolomic Study on Idiosyncratic Liver Injury Induced by Different Extracts of Polygonum multiflorum in Rats Integrated with Pattern Recognition and Enriched Pathways AnalysisIdiosyncratic Drug-Induced Liver Injury (IDILI): Potential Mechanisms and Predictive Assays.An Update on Drug-induced Liver Injury.Trovafloxacin potentiation of lipopolysaccharide-induced tumor necrosis factor release from RAW 264.7 cells requires extracellular signal-regulated kinase and c-Jun N-Terminal Kinase.Animal models of idiosyncratic drug-induced liver injury--current status.Role of immune reactions in drug-induced liver injury (DILI).An evaluation of the latest in vitro tools for drug metabolism studies.Hepatotoxicity mechanisms of isoniazid: A mini-review.Hepatotoxicity of New Oral Anticoagulants (NOACs).Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs.Current limitations and future opportunities for prediction of DILI from in vitro.The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development.Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen.Opportunities and challenges in the wider adoption of liver and interconnected microphysiological systems.Current challenges and controversies in drug-induced liver injury.Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum multiflorum.Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study.Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity.Understanding drug-cytokine synergistic toxicity.Nonalcoholic Fatty Liver Disease Is a Susceptibility Factor for Perchloroethylene-Induced Liver Effects in Mice.Idiosyncratic Drug-Induced Liver Injury Due to Ciprofloxacin: A Report of Two Cases and Review of the Literature
P2860
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P2860
Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@ast
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@en
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@nl
type
label
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@ast
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@en
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@nl
prefLabel
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@ast
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@en
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@nl
P2093
P2860
P356
P1476
Idiosyncratic drug-induced liv ...... f trovafloxacin hepatotoxicity
@en
P2093
Patricia E Ganey
Patrick J Shaw
Robert A Roth
P2860
P356
10.1093/TOXSCI/KFQ168
P577
2010-06-10T00:00:00Z