Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation. - Wikidata - wikimedia - TriplyDB

Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation.

Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation.

http://www.wikidata.org/entity/Q34201034

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Regulation of pulmonary fibrosis by chemokine receptor CXCR3 Chemokine blockade: a new era in the treatment of rheumatoid arthritis?CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritis.T Cell Interstitial Migration: Motility Cues from the Inflamed Tissue for Micro- and Macro-Positioning The blood-brain-barrier in multiple sclerosis: functional roles and therapeutic targeting Peptide vaccination in Montanide adjuvant induces and GM-CSF increases CXCR3 and cutaneous lymphocyte antigen expression by tumor antigen-specific CD8 T cells.Endothelial TNF receptor 2 induces IRF1 transcription factor-dependent interferon-β autocrine signaling to promote monocyte recruitment.The role of CXCR3 in DSS-induced colitis.Specificity tuning of antibody fragments to neutralize two human chemokines with a single agent CXCR3 and its ligands participate in the host response to Bordetella bronchiseptica infection of the mouse respiratory tract but are not required for clearance of bacteria from the lung Peritoneal cavity is dominated by IFNγ-secreting CXCR3+ Th1 cells.Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response.Protein-protein interaction network and mechanism analysis in ischemic stroke CXCR3 in T cell function.Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells KLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells.The role of CXCR3 in the induction of primary biliary cirrhosis.CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells.Preferential type 1 chemokine receptors and cytokine production of CD28- T cells in ankylosing spondylitis.Differential effect of methotrexate on the increased CCR2 density on circulating CD4 T lymphocytes and monocytes in active chronic rheumatoid arthritis, with a down regulation only on monocytes in responders Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: implication of differing roles for IP-10.Emerging candidates in breast cancer stem cell maintenance, therapy resistance and relapse.Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium.Evidence for differential roles for NKG2D receptor signaling in innate host defense against coronavirus-induced neurological and liver disease.CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease.Targeting CXCR2 enhances chemotherapeutic response, inhibits mammary tumor growth, angiogenesis, and lung metastasis.Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10 T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors.Chemokine receptor antagonists: part 2.Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung CXCR3 ligands: redundant, collaborative and antagonistic functions.Innate immunity in the respiratory epithelium.Chemokine receptors in psoriasis.Mechanisms of diabetic autoimmunity: II--Is diabetes a central or peripheral disorder of effector and regulatory cells?Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12.Chemokine receptor CXCR3 deficiency exacerbates murine autoimmune cholangitis by promoting pathogenic CD8+ T cell activation.WSX-1 signalling inhibits CD4⁺ T cell migration to the liver during malaria infection by repressing chemokine-independent pathways A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6.

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Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation.

http://www.wikidata.org/entity/Q34201034

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Journal of Leukocyte Biology

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Antibody-mediated blockade of ...... ls into sites of inflammation.

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P2093

Greg E Koch

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Jenny H Xie

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Jerry Di Salvo

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John Mudgett

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Julie A DeMartino

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Laurence B Peterson

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Linda S Wicker

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Min Lu

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Naomi Nomura

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Raymond Rosa

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P2860

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions

Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3

Requirement of the chemokine receptor CXCR3 for acute allograft rejection

Chemokines and disease

Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors

T-Cell Function and Migration — Two Sides of the Same Coin

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

Lymphocyte homing and homeostasis

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771-780

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10.1189/JLB.1102573

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6

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73

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2003-06-01T00:00:00Z

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277499688

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12773510

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