Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype. - Wikidata - wikimedia - TriplyDB

Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype.

Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype.

http://www.wikidata.org/entity/Q34204333

about

Cancer drug resistance: redox resetting renders a way The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1 Side population cells as prototype of chemoresistant, tumor-initiating cells Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies The complexity of the Nrf2 pathway: beyond the antioxidant response Cytoprotection "gone astray": Nrf2 and its role in cancer Elevated expression of Nrf2 mediates multidrug resistance in CD133(+) head and neck squamous cell carcinoma stem cells Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer Down-regulation of the placental BCRP/ABCG2 transporter in response to hypoxia signaling.Regulation of voltage-gated potassium channels attenuates resistance of side-population cells to gefitinib in the human lung cancer cell line NCI-H460 Kinetic Modeling of ABCG2 Transporter Heterogeneity: A Quantitative, Single-Cell Analysis of the Side Population Assay.A synthetic chalcone as a potent inducer of glutathione biosynthesis Genetic polymorphism in the NRF2 gene as a prognosis marker for cancer chemotherapy.Cisplatin in 5% Ethanol Eradicates Cisplatin-Resistant Lung Tumor by Killing Lung Cancer Side Population (SP) Cells and Non-SP Cells.SNP (-617C>A) in ARE-like loci of the NRF2 gene: a new biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women.Frequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.miR-99a directly targets the mTOR signalling pathway in breast cancer side population cells.Activation of NRF2 by p62 and proteasome reduction in sphere-forming breast carcinoma cells.Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors.Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.The involvement of NRF2 in lung cancer Understanding the role of NRF2-regulated miRNAs in human malignancies.Involvement of NRF2 Signaling in Doxorubicin Resistance of Cancer Stem Cell-Enriched Colonospheres.ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity.YAP1 regulates ABCG2 and cancer cell side population in human lung cancer cells.Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression.Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.Human ABCG2: structure, function, and its role in multidrug resistance.Lung cancer stem cells: tumor biology and clinical implications.Inflammation and pancreatic cancer: disease promoter and new therapeutic target.Nrf2: bane or blessing in cancer?Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.Differential impact of flavonoids on redox modulation, bioenergetics and cell signalling in normal and tumor cells: a comprehensive review.ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells.Cell-type selective phototoxicity achieved with chlorophyll-a derived photosensitizers in a co-culture system of primary human tumor and normal lung cells.Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters.

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P2860

Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype.

http://www.wikidata.org/entity/Q34204333

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Expression of ABCG2 (BCRP) is ...... and chemoresistance phenotype.

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Expression of ABCG2 (BCRP) is ...... and chemoresistance phenotype.

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Expression of ABCG2

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type

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Expression of ABCG2 (BCRP) is ...... and chemoresistance phenotype.

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Expression of ABCG2 (BCRP) is ...... and chemoresistance phenotype.

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Expression of ABCG2

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Expression of ABCG2 (BCRP) is ...... and chemoresistance phenotype.

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Expression of ABCG2 (BCRP) is ...... and chemoresistance phenotype.

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Expression of ABCG2

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1535-7163.MCT-10-0108

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Molecular Cancer Therapeutics

P1476

Expression of ABCG2 (BCRP) is ...... and chemoresistance phenotype.

@en

P2093

Anju Singh

http://www.w3.org/2001/XMLSchema#string

Christine Happel

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Hailong Wu

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Jinfang Ma

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Ping Zhang

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Shyam Biswal

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P2860

A multidrug resistance transporter from human MCF-7 breast cancer cells

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

A distinct "side population" of cells with high drug efflux capacity in human tumor cells

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

Cancer statistics, 2008

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

The consensus coding sequences of human breast and colorectal cancers

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

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2365-2376

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scholarly article

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10.1158/1535-7163.MCT-10-0108

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8

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9

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45493993

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20682644

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2955865

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