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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

http://www.wikidata.org/entity/Q34205126

about

The evolution of genome-scale models of cancer metabolism Links between metabolism and cancer Clinical significance of T cell metabolic reprogramming in cancer Fundamentals of cancer metabolism MicroRNAs and oncogenic transcriptional regulatory networks controlling metabolic reprogramming in cancers Cancer Metabolism: A Modeling Perspective Targeting amino acid metabolism in cancer growth and anti-tumor immune response 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling Cancer Metabolism and Drug Resistance Dysregulated metabolism contributes to oncogenesis Amino acid management in cancer Serine, glycine and one-carbon units: cancer metabolism in full circle Serine and glycine metabolism in cancer Defining the metabolome: size, flux, and regulation Pathways and therapeutic targets in melanoma Genetically-defined metabolic reprogramming in cancer Redox control of glutamine utilization in cancer Cancer cell metabolism: implications for therapeutic targets Fueling immunity: insights into metabolism and lymphocyte function Stretching morphogenesis of the roof plate and formation of the central canal Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1 Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy Serine is a natural ligand and allosteric activator of pyruvate kinase M2 Free Glycine Accelerates the Autoproteolytic Activation of Human Asparaginase Metabolic rewiring in melanoma Undercover: gene control by metabolites and metabolic enzymes Metabolomic profiling of hormone-dependent cancers: a bird's eye view Metabolic pathways promoting cancer cell survival and growth A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels Lin28: primal regulator of growth and metabolism in stem cells The Intercellular Metabolic Interplay between Tumor and Immune Cells Metabolomic profiling from formalin-fixed, paraffin-embedded tumor tissue using targeted LC/MS/MS: application in sarcoma Discovery of novel allosteric effectors based on the predicted allosteric sites for Escherichia coli D-3-phosphoglycerate dehydrogenase TIGAR is required for efficient intestinal regeneration and tumorigenesis Activation of β-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant response Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra Six Hours after Infection, the Metabolic Changes Induced by WSSV Neutralize the Host's Oxidative Stress Defenses KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism Metabolic reprogramming: a cancer hallmark even warburg did not anticipate The intrinsic disorder alphabet. III. Dual personality of serine.

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P2860

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

http://www.wikidata.org/entity/Q34205126

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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type

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

@en

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

@nl

prefLabel

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

@ast

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

@en

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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Nature Genetics

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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Adam J Bass

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Alexandra R Grassian

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Andrea L Richardson

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Atsuo T Sasaki

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Azra H Ligon

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Christian M Metallo

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Costas A Lyssiotis

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Edouard Mullarky

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Gerhard Wagner

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Gregory Heffron

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Understanding the Warburg effect: the metabolic requirements of cell proliferation

An integrated genomic analysis of human glioblastoma multiforme

Pyruvate kinase M2 is a phosphotyrosine-binding protein

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

ONCOMINE: a cancer microarray database and integrated data-mining platform

X chromosomal abnormalities in basal-like human breast cancer

Cloning, sequencing and expression of rat liver 3-phosphoglycerate dehydrogenase

Triple-Negative Breast Cancer

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

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869-874

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10.1038/NG.890

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9

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43

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Lewis C. Cantley

Jason W. Locasale

Matthew Meyerson

Dimitrios Anastasiou

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2011-07-31T00:00:00Z

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51535807

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21804546

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3677549

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