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Patient-derived xenograft models: an emerging platform for translational cancer research

Patient-derived xenograft models: an emerging platform for translational cancer research

http://www.wikidata.org/entity/Q34205518

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Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review Animal Models of Uveal Melanoma: Methods, Applicability, and Limitations Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs Bioengineering Models for Breast Cancer Research VEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedside From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts New concepts and challenges in the clinical translation of cancer preventive therapies: the role of pharmacodynamic biomarkers Molecular and clinical implementations of ovarian cancer mouse avatar models Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts Cancer evolution: mathematical models and computational inference Patient-derived xenograft models of breast cancer and their predictive power Preclinical mouse cancer models: a maze of opportunities and challenges.Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.Patient-derived xenografts: a relevant preclinical model for drug development Approaches to modernize the combination drug development paradigm Using Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer Therapy Genetically engineered mouse models in oncology research and cancer medicine Patient-derived tumour xenografts for breast cancer drug discovery Organoid development in cancer genome discovery Prioritizing therapeutic targets using patient-derived xenograft models Metformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived Xenografts A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds Translating genomic profiling to gastrointestinal cancer treatment.Imaging biomarker roadmap for cancer studies TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis The future of patient-derived tumor xenografts in cancer treatment.Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new co-clinical model for treatment optimization.In vivo models in breast cancer research: progress, challenges and future directions.Gastric Cancer in the Era of Precision Medicine.Hepatocyte Growth Factor/c-Met Signaling in Head and Neck Cancer and Implications for Treatment Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis.Ex vivo tumor culture systems for functional drug testing and therapy response prediction Establishment of an orthotopic patient-derived xenograft mouse model using uveal melanoma hepatic metastasis Prevention of Human Lymphoproliferative Tumor Formation in Ovarian Cancer Patient-Derived Xenografts.Optimizing mouse models for precision cancer prevention.PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2.Hippo pathway mediates resistance to cytotoxic drugs.

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P2860

Patient-derived xenograft models: an emerging platform for translational cancer research

http://www.wikidata.org/entity/Q34205518

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2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Patient-derived xenograft models: an emerging platform for translational cancer research

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2159-8290.CD-14-0001

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Cancer Discovery

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Patient-derived xenograft models: an emerging platform for translational cancer research

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Alberto Villanueva

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Carlos Caldas

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Eva Budinská

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Frederic Amant

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Gunhild Mari Mælandsmo

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Jos Jonkers

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Livio Trusolino

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Steven de Jong

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P2860

Molecular profiling of patient-derived breast cancer xenografts

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

Patient-derived tumour xenografts as models for oncology drug development

Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Patient-derived tumor xenografts: transforming clinical samples into mouse models

Single-cell dissection of transcriptional heterogeneity in human colon tumors

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

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10.1158/2159-8290.CD-14-0001

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9

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4

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Robert B. Clarke

Sergio Roman-Roman

Annette T. Byrne

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2014-07-15T00:00:00Z

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25185190

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4167608

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