Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit - Wikidata - wikimedia - TriplyDB

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

http://www.wikidata.org/entity/Q34206033

about

Melanocortin 1 Receptor: Structure, Function, and Regulation UV signaling pathways within the skin UV radiation and the skin Differentiated melanocyte cell division occurs in vivo and is promoted by mutations in Mitf.PGC-1 coactivators regulate MITF and the tanning response.Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation.Pharmacologic induction of epidermal melanin and protection against sunburn in a humanized mouse model.The three M's: melanoma, microphthalmia-associated transcription factor and microRNA.MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation The roles of microphthalmia-associated transcription factor and pigmentation in melanoma.Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis.Paracrine regulation of melanocyte genomic stability: a focus on nucleotide excision repair.A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin.Effect of MC1R variant allele status on MSH-ligand induction of dopachrome tautomerase in melanocytes co-cultured with keratinocytes.Protein kinase A activation inhibits oncogenic Sonic hedgehog signalling and suppresses basal cell carcinoma of the skin.RAF-isotype switching: from B to C through PDE.In vitro induction of melanin synthesis and extrusion by tamoxifen.Getting a tan without getting SIK.FOXQ1 controls the induced differentiation of melanocytic cells.A Topical Solution to the Sunless Tanning Problem.PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma.Effects of multi-polar radiofrequency and pulsed electromagnetic field treatment in Koreans: case series and survey study.A Convergence-Based Framework for Cancer Drug Resistance.α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis.Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.

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Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

http://www.wikidata.org/entity/Q34206033

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@ast

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@en

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@nl

type

label

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@ast

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

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Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@nl

prefLabel

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@ast

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@en

Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

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Genes & Development

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Control of melanocyte differentiation by a MITF-PDE4D3 homeostatic circuit

@en

P2093

Carmit Levy

http://www.w3.org/2001/XMLSchema#string

David E Fisher

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Mehdi Khaled

http://www.w3.org/2001/XMLSchema#string

P2860

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

MITF: master regulator of melanocyte development and melanoma oncogene

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF

Novel MITF targets identified using a two-step DNA microarray strategy

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives.

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.

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2276-2281

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scholarly article

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10.1101/GAD.1937710

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20

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24

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2010-10-01T00:00:00Z

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20952536

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2956206

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