Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response - Wikidata - wikimedia - TriplyDB

Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response

Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response

http://www.wikidata.org/entity/Q34206321

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Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion.Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.Hypothalamic stem cells control ageing speed partly through exosomal miRNAs.Hypothalamic microinflammation: a common basis of metabolic syndrome and aging.SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise.Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1.Persimmon vinegar ripening with the mountain-cultivated ginseng ingestion reduces blood lipids and lowers inflammatory cytokines in obese adolescents Rapid linkage of innate immunological signals to adaptive immunity by the brain-fat axis.Epigenomic and metabolic responses of hypothalamic POMC neurons to gestational nicotine exposure in adult offspring Hypothalamic inflammation and gliosis in obesity FTO modulates fibrogenic responses in obstructive nephropathy.Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model.Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders.Central Leptin and Tumor Necrosis Factor-α (TNFα) in Diurnal Control of Blood Pressure and Hypertension Neuroinflammatory and autonomic mechanisms in diabetes and hypertension.TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle.Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury.High-protein diet promotes sensitivity to cholecystokinin and shifts the cecal microbiome without altering brain inflammation in diet-induced obesity in rats.Inhibitors of DNA methylation support TGF-β1-induced IL11 expression in gingival fibroblasts.The pathophysiology of defective proteostasis in the hypothalamus - from obesity to ageing.Age-Dependent Changes in the Activation and Regulation of Microglia.NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis.Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain.Characterization of metabolic health in mouse models of fibrillin-1 perturbation.Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype.Chronic exercise reduces hypothalamic transforming growth factor-β1 in middle-aged obese mice.Role of TGFβ signaling in the pathogenesis of Alzheimer's disease.Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight.Age-Dependent Neurochemical Remodeling of Hypothalamic Astrocytes.Hypothalamic Dysfunction in Obesity and Metabolic Disorders.Hypothalamic inflammation in obesity and metabolic disease.Obesity-associated extracellular mtDNA activates central TGFβ pathway to cause blood pressure increase.Neural Programmatic Role of Leptin, TNFα, Melanocortin, and Glutamate in Blood Pressure Regulation vs Obesity-Related Hypertension in Male C57BL/6 Mice.

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Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response

http://www.wikidata.org/entity/Q34206321

description

2014 nî lūn-bûn

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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Dongsheng Cai

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Hai Zhang

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Jingqi Yan

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Juxue Li

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Lianxi Li

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Sudarshana Purkayastha

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Ye Yin

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Yizhe Tang

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P2860

Neuroinflammatory basis of metabolic syndrome

IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

Transforming growth factor-beta induces development of the T(H)17 lineage

Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

Transforming growth factor-beta regulation of immune responses

Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity

Shared principles in NF-kappaB signaling

Stress granules: the Tao of RNA triage

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