SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling. - Wikidata - wikimedia - TriplyDB

SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling.

SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling.

http://www.wikidata.org/entity/Q34211024

about

Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein SOCS, inflammation, and cancer SOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune Function Twist-2 controls myeloid lineage development and function Immunosuppressive strategies that are mediated by tumor cells p38 MAPK-inhibited dendritic cells induce superior antitumour immune responses and overcome regulatory T-cell-mediated immunosuppression.Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus.Tumor immunology and cancer immunotherapy: summary of the 2013 SITC primer.Molecular control of steady-state dendritic cell maturation and immune homeostasis.Regulatory effect of microRNA-135a on the Th1/Th2 imbalance in a murine model of allergic rhinitis A20 controls macrophage to elicit potent cytotoxic CD4(+) T cell response.A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1.IRAK-M removal counteracts dendritic cell vaccine deficits in migration and longevity.Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice.A phase II study evaluating the safety and efficacy of an adenovirus-ΔLMP1-LMP2 transduced dendritic cell vaccine in patients with advanced metastatic nasopharyngeal carcinoma.A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner.SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages Enhancement of dendritic cells as vaccines for cancer Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins.A novel cyclic helix B peptide inhibits dendritic cell maturation during amelioration of acute kidney graft rejection through Jak-2/STAT3/SOCS1.MicroRNA-155 induces differentiation of RAW264.7 cells into dendritic-like cells.Enhanced anti-tumor activity of interferon-alpha in SOCS1-deficient mice is mediated by CD4⁺ and CD8⁺ T cells.Suppressor of cytokine signaling 1 inhibition strategy to enhance anti-HIV vaccination.Helminth excreted/secreted antigens repress expression of LPS-induced Let-7i but not miR-146a and miR-155 in human dendritic cells.Antigen choice determines vaccine-induced generation of immunogenic versus tolerogenic dendritic cells that are marked by differential expression of pancreatic enzymes.Immunological research using RNA interference technology.Regulation of dendritic cells by female sex steroids: relevance to immunity and autoimmunity.A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression.CD8+ T-cell responses against hemoglobin-beta prevent solid tumor growth.Autoimmunity stimulated by adoptively transferred dendritic cells is initiated by both alphabeta and gammadelta T cells but does not require MyD88 signaling.An effective vaccination approach augments anti-HIV systemic and vaginal immunity in mice with decreased HIV-1 susceptible α4β7high CD4+ T cells.A paradigm shift in therapeutic vaccination of cancer patients: the need to apply therapeutic vaccination strategies in the preventive setting.Targeting intracellular signaling: a novel approach to vaccination.Dendritic cell vaccination and immune monitoring.Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.SOCS1 downregulation in dendritic cells promotes memory T-cell responses.Regulation of interferon gamma signaling by suppressors of cytokine signaling and regulatory T cells.Dendritic cell-based immunotherapy for myeloid leukemias.

P2860

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P2860

SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling.

http://www.wikidata.org/entity/Q34211024

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

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2005年論文

@zh-hk

2005年論文

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2005年論文

@zh-tw

2005年论文

@wuu

name

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@ast

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@en

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@nl

type

label

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@ast

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@en

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@nl

prefLabel

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@ast

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@en

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@nl

P1433

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P2860

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P1433

Journal of Clinical Investigation

P1476

SOCS1 restricts dendritic cell ...... L-12 production and signaling.

@en

P2093

Kevin Evel-Kabler

http://www.w3.org/2001/XMLSchema#string

Melissa Aldrich

http://www.w3.org/2001/XMLSchema#string

Si-Yi Chen

http://www.w3.org/2001/XMLSchema#string

Xiao-Tong Song

http://www.w3.org/2001/XMLSchema#string

Xue F Huang

http://www.w3.org/2001/XMLSchema#string

P2860

Cancer immunotherapy: moving beyond current vaccines

Toll-like receptor signalling

Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells

Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

Innate immune recognition

Dendritic cells and the control of immunity

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection

Interleukin-12 and the regulation of innate resistance and adaptive immunity

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90-100

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scholarly article

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10.1172/JCI26169

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P433

1

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116

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2005-12-15T00:00:00Z

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7412194

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16357940

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1312019

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