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Diversification of TAM receptor tyrosine kinase function

Diversification of TAM receptor tyrosine kinase function

http://www.wikidata.org/entity/Q34214465

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The role of airway macrophages in apoptotic cell clearance following acute and chronic lung inflammation The Elusive Antifibrotic Macrophage Discovering Molecules That Regulate Efferocytosis Using Primary Human Macrophages and High Content Imaging The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response Phagocytosis of apoptotic cells in homeostasis Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo Apoptotic cell recognition receptors and scavenger receptors.TAM receptors regulate multiple features of microglial physiology Association of plasma levels of Protein S with disease severity in multiple sclerosis.Engulfment signals and the phagocytic machinery for apoptotic cell clearance.MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.Camouflage and misdirection: the full-on assault of ebola virus disease Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis Regulation of macrophage development and function in peripheral tissues Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.TAM receptor deficiency affects adult hippocampal neurogenesis.The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis.TAM receptor signaling in immune homeostasis.Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib.Study of Early Elevated Gas6 Plasma Level as a Predictor of Mortality in a Prospective Cohort of Patients with Sepsis Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells.Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16(+) monocyte population via the IL-10/STAT3 axis.The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity Apoptotic cell clearance of Leishmania major-infected neutrophils by dendritic cells inhibits CD8⁺ T-cell priming in vitro by Mer tyrosine kinase-dependent signaling The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of Platelet Microparticles.Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Behçet's disease.Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivo Apoptotic CD8 T-lymphocytes disable macrophage-mediated immunity to Trypanosoma cruzi infection.AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity.The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation.Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny Deficiency of AXL in Bone Marrow-Derived Cells Does Not Affect Advanced Atherosclerotic Lesion Progression

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Diversification of TAM receptor tyrosine kinase function

http://www.wikidata.org/entity/Q34214465

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Diversification of TAM receptor tyrosine kinase function

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Diversification of TAM receptor tyrosine kinase function

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Diversification of TAM receptor tyrosine kinase function

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type

label

Diversification of TAM receptor tyrosine kinase function

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Diversification of TAM receptor tyrosine kinase function

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Diversification of TAM receptor tyrosine kinase function

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Diversification of TAM receptor tyrosine kinase function

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Diversification of TAM receptor tyrosine kinase function

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Diversification of TAM receptor tyrosine kinase function

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Nature Immunology

P1476

Diversification of TAM receptor tyrosine kinase function

@en

P2093

Anna Zagórska

http://www.w3.org/2001/XMLSchema#string

Erin D Lew

http://www.w3.org/2001/XMLSchema#string

Greg Lemke

http://www.w3.org/2001/XMLSchema#string

Paqui G Través

http://www.w3.org/2001/XMLSchema#string

P2860

Cell signaling by receptor tyrosine kinases

Direct demonstration that receptor crosslinking or aggregation is important in insulin action

The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry.

PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance

Exploring the full spectrum of macrophage activation

Circadian control of the immune system

Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily

The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage

Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells

Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family

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920-928

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scholarly article

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10.1038/NI.2986

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10

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15

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2014-09-07T00:00:00Z

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265391784

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25194421

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4169336

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