Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function.
about
Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacologyHepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 geneIndividualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.The role of genetic factors and kidney and liver function in glycemic control in type 2 diabetes patients on long-term metformin and sulphonylurea cotreatment.Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South AfricaColorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene.SLC22A1-ABCB1 haplotype profiles predict imatinib pharmacokinetics in Asian patients with chronic myeloid leukemia.Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1.Pharmacogenetics in type 2 diabetes: potential implications for clinical practiceInfluences of organic cation transporter polymorphisms on the population pharmacokinetics of metformin in healthy subjects.Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes.Disposition of metformin: variability due to polymorphisms of organic cation transporters.Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability - considerations for drug development.Renal transport of organic anions and cations.Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses, and drug-drug interactions.Loops and layers of post-translational modifications of drug transporters.Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics.Mechanistic models describing active renal reabsorption and secretion: a simulation-based study.Evaluation of para-Aminosalicylic Acid as a Substrate of Multiple Solute Carrier Uptake Transporters and Possible Drug Interactions with Nonsteroidal Anti-inflammatory Drugs In Vitro.Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients.Inter-Subject Variability in OCT1 Activity in 27 Batches of Cryopreserved Human Hepatocytes and Association with OCT1 mRNA Expression and Genotype.A review of the literature on the relationships between genetic polymorphisms and chemotherapy-induced nausea and vomiting.Evaluation of the potential interaction between tofacitinib and drugs that undergo renal tubular secretion using metformin, an in vivo marker of renal organic cation transporter 2.Metformin resistance alleles in polycystic ovary syndrome: pattern and association with glucose metabolism.
P2860
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P2860
Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Genetic polymorphisms in organ ...... ions exhibit altered function.
@ast
Genetic polymorphisms in organ ...... ions exhibit altered function.
@en
Genetic polymorphisms in organic cation transporter 1
@nl
type
label
Genetic polymorphisms in organ ...... ions exhibit altered function.
@ast
Genetic polymorphisms in organ ...... ions exhibit altered function.
@en
Genetic polymorphisms in organic cation transporter 1
@nl
prefLabel
Genetic polymorphisms in organ ...... ions exhibit altered function.
@ast
Genetic polymorphisms in organ ...... ions exhibit altered function.
@en
Genetic polymorphisms in organic cation transporter 1
@nl
P2093
P2860
P356
P1476
Genetic polymorphisms in organ ...... ions exhibit altered function.
@en
P2093
Andej Sali
Avner Schlessinger
Eugene Chen
Ji Ha Choi
Julie Segenthelar
Kathleen M Giacomini
Ligong Chen
Michiaki Kubo
Miho Takizawa
Naoko Iwasaki
P2860
P356
10.1124/JPET.110.170159
P407
P577
2010-07-16T00:00:00Z