The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline.
about
Proteomics and peptidomics: moving toward precision medicine in urological malignanciesPorous bead-based diagnostic platforms: bridging the gaps in healthcareOverview of proteomics studies in obstructive sleep apneaApplications of targeted proteomics in systems biology and translational medicineProteomics investigations of HDL: challenges and promiseTargeted proteomics for biomarker discovery and validation of hepatocellular carcinoma in hepatitis C infected patientsDeveloping multiplexed assays for troponin I and interleukin-33 in plasma by peptide immunoaffinity enrichment and targeted mass spectrometryDetermination of variation parameters as a crucial step in designing TMT-based clinical proteomics experimentsAn automated and multiplexed method for high throughput peptide immunoaffinity enrichment and multiple reaction monitoring mass spectrometry-based quantification of protein biomarkers.Reconstructing the pipeline by introducing multiplexed multiple reaction monitoring mass spectrometry for cancer biomarker verification: an NCI-CPTC initiative perspective.Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance.Applying proteomics to the diagnosis and treatment of ALS and related diseases.Automated screening of monoclonal antibodies for SISCAPA assays using a magnetic bead processor and liquid chromatography-selected reaction monitoring-mass spectrometry.Recent cerebrospinal fluid biomarker studies of Alzheimer's disease.Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.Towards proteome standards: the use of absolute quantitation in high-throughput biomarker discovery.Selective enrichment and sensitive detection of peptide and protein biomarkers in human serum using polymeric reverse micelles and MALDI-MSThe evolving role of mass spectrometry in cancer biomarker discoveryMass-spectrometry-based clinical proteomics--a review and prospective.Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics.Ensembles of protein termini and specific proteolytic signatures as candidate biomarkers of disease.Restructuring proteomics through verificationProtein analysis by shotgun/bottom-up proteomicsThe importance of early life in childhood obesity and related diseases: a report from the 2014 Gravida Strategic SummitComputational biomarker pipeline from discovery to clinical implementation: plasma proteomic biomarkers for cardiac transplantation.Evaluation of large scale quantitative proteomic assay development using peptide affinity-based mass spectrometry.Identification of a novel proteoform of prostate specific antigen (SNP-L132I) in clinical samples by multiple reaction monitoringBiomarker discovery for early detection of hepatocellular carcinoma in hepatitis C-infected patients.Simultaneous quantification of apolipoprotein A-I and apolipoprotein B by liquid-chromatography-multiple- reaction-monitoring mass spectrometryFrom lost in translation to paradise found: enabling protein biomarker method transfer by mass spectrometryAnti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA.Biomarkers: hopes and challenges in the path from discovery to clinical practice.Using data-independent, high-resolution mass spectrometry in protein biomarker research: perspectives and clinical applications.A targeted proteomics-based pipeline for verification of biomarkers in plasmaAccurate quantification of cardiovascular biomarkers in serum using Protein Standard Absolute Quantification (PSAQ™) and selected reaction monitoringTargeted proteomics: a bridge between discovery and validation.A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease.Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasmaSerum Glycoprotein Biomarker Discovery and Qualification Pipeline Reveals Novel Diagnostic Biomarker Candidates for Esophageal Adenocarcinoma.
P2860
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P2860
The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The interface between biomarke ...... he protein biomarker pipeline.
@ast
The interface between biomarke ...... he protein biomarker pipeline.
@en
The interface between biomarke ...... he protein biomarker pipeline.
@nl
type
label
The interface between biomarke ...... he protein biomarker pipeline.
@ast
The interface between biomarke ...... he protein biomarker pipeline.
@en
The interface between biomarke ...... he protein biomarker pipeline.
@nl
prefLabel
The interface between biomarke ...... he protein biomarker pipeline.
@ast
The interface between biomarke ...... he protein biomarker pipeline.
@en
The interface between biomarke ...... he protein biomarker pipeline.
@nl
P2093
P2860
P356
P1476
The interface between biomarke ...... he protein biomarker pipeline.
@en
P2093
Amanda G Paulovich
Jeffrey R Whiteaker
P2860
P304
P356
10.1002/PRCA.200780174
P577
2008-10-01T00:00:00Z