Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
about
Purification and specificity of a human microsomal epoxide hydratasePurification and propeties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putidaDecreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiolThe 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic painMicrosomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human diseaseMammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.Rat and human liver cytosolic epoxide hydrolases: evidence for multiple forms at level of protein and mRNAAntiepileptic drugs: biotransformation, metabolism, and serum half-life.An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.Oral toxicity of 1,1-dichloroethylene in the rat: effects of sex, age, and fastingSpecific positions involved in enzyme catalyzed covalent binding of benzo[a]pyrene to poly(G).Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite.Epoxidation reactions catalyzed by rat liver cytochromes P-450 and P-448 occur at different faces of the 8,9-double bond of 8-methylbenz[a]anthracene.Unusual regioselectivity and active site topology of human cytochrome P450 2J2Nitrofurantoin cytotoxicity. In vitro assessment of risk based on glutathione metabolism.Effects of modifying structure on electrophilic reactions with biological nucleophiles.Chemical reactivity, biotransformation, and toxicity of polychlorinated aliphatic compounds.The low reactivity of 5H-dibenzo[a, d]cycloheptene 10,11-oxide in microsomal epoxide hydrolase catalysed hydration.The epoxide-diol pathway in the metabolism of vinylbital in rat and man.Mechanism-based predictions of interactions.Stimulation of mammalian epoxide hydrase activity by flavones.K-region epoxides of polycyclic hydrocarbons: formation and further metabolism of benz (a) anthracene 5,6-oxide by human lung preparations.The metabolic fate of 1',2'-epoxyhexobarbital in the rat.Biotransformation of xenobiotics in Drosophila melanogaster and its relevance for mutagenicity testing.Stereospecific hydrolysis of 8 alpha,9 alpha- and 8 beta,9 beta-epoxyhexahydrocannabinols in the mouse in vivo and in vitro.Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin modelsEnhancement of 1,1-Dichloroethylene Toxicity by Pretreatment of Fasted Male Rats with 2,3-Epoxypropan-1-01Reduction of benzo(a)pyrene mutagenicity by dihydrodiol dehydrogenase
P2860
Q24531419-5B4E7680-FE04-4015-B219-6CFE9BA80263Q24644241-D2492E46-188A-483D-A6D4-4425334ED579Q28332792-5A88E2A8-EA8A-4487-8ABC-47B28A48A393Q28392416-31A39080-CEC7-4A9E-AEA6-F3147308FE89Q28608628-AD8A8F5D-4EDC-4BF2-83E9-F8CE72E0FA22Q34213703-E3D3D9AC-2777-47D5-8B4B-38FFD3281937Q34313646-968BD394-8A0D-4826-9472-5DD7942353ADQ34359667-4867FC06-3B3A-4606-B3AF-DBA90830C28CQ34418371-F278CF2C-D0EA-4A49-A7CC-D014B1C6635FQ34664359-2AE450D0-FE8B-47FA-B77C-34F788BFA73CQ34996242-20B44A89-90C5-4F61-A3FA-0A61435E9FDBQ35353384-A6AF4964-B0F4-4EC0-90DF-6501F86089CFQ36320140-B0E94201-2AA4-4D9B-82CF-7606ACE55307Q36648643-3F2611B1-C04B-4831-A727-B2927070FA31Q37025399-FA421349-4186-4254-958A-E21F0C5756F5Q40203327-76715AAD-275E-40DC-81EC-4A8C3731D086Q40625551-3D7BBDA2-9F01-4346-864C-B55881AF0E16Q42198505-64E84A69-932D-4C41-9220-6658420BFA02Q42241086-B4ED7E52-0A45-40E5-860F-392DDE7C4911Q42269185-189729B4-1CEB-42BB-A5AC-B94E29949F4CQ42272911-21EF7F77-C8F5-441A-BBC4-FE52A28EA10CQ43898573-C1AA0B9D-9D3E-4D6B-999E-B8A02B8866B1Q50216145-09091092-F44B-4035-BFEA-AC4747C0D21CQ53579672-07A245E6-DD7A-48D7-B3B5-6E181A85A05BQ54454361-5D61D418-88A5-4D1B-A235-3D5843B49AA4Q57095660-00030149-D386-4C20-8EF3-D88D266BB7AFQ57383707-D2A34C08-C03E-4952-AE8F-5A60CD28BCDFQ59089154-FD210ABA-6A50-4B7F-BD31-756AB36215A6
P2860
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
description
1971 nî lūn-bûn
@nan
1971 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1971 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1971年の論文
@ja
1971年論文
@yue
1971年論文
@zh-hant
1971年論文
@zh-hk
1971年論文
@zh-mo
1971年論文
@zh-tw
1971年论文
@wuu
name
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@ast
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@en
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@nl
type
label
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@ast
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@en
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@nl
prefLabel
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@ast
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@en
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@nl
P2093
P356
P1433
P1476
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.
@en
P2093
P304
P356
10.1021/BI00802A005
P407
P577
1971-12-01T00:00:00Z