SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass - Wikidata - wikimedia - TriplyDB

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

http://www.wikidata.org/entity/Q34232012

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Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Biochemical Genetic Pathways that Modulate Aging in Multiple Species Risk determination and prevention of breast cancer Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2.Sirtuin1 (Sirt1) promotes cortical bone formation by preventing β-catenin sequestration by FoxO transcription factors in osteoblast progenitors.A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.Mitochondrial dysfunction and insulin resistance: an update.The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells Macronutrients and caloric intake in health and longevity Cerebral Perfusion Enhancing Interventions: A New Strategy for the Prevention of Alzheimer Dementia.Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.Histone Deacetylases in Bone Development and Skeletal Disorders.Protective effects of sirtuins in cardiovascular diseases: from bench to bedside Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes.Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.Strategies and Challenges in Clinical Trials Targeting Human Aging.Muscle wasting in end-stage renal disease promulgates premature death: established, emerging and potential novel treatment strategies.Novel investigational drugs mimicking exercise for the treatment of cachexia.Telomeres, Nutrition, and Longevity: Can We Really Navigate Our Aging?The impact of low-protein high-carbohydrate diets on aging and lifespan.SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms.Translating the Science of Aging into Therapeutic Interventions.The dog aging project: translational geroscience in companion animals.Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis.Emerging drugs affecting skeletal muscle function and mitochondrial biogenesis - Potential implications for sports drug testing programs.Key proteins and pathways that regulate lifespan.Sirtuins, a promising target in slowing down the ageing process.The role of epigenetics in renal ageing.SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis.The Role of Sirtuins in Antioxidant and Redox Signaling.Sarcopenia, aging and prospective interventional strategies.A need for NAD+ in muscle development, homeostasis, and aging.Biophysical characterization of hit compounds for mechanism-based enzyme activation.Future directions of resveratrol research.Modulating Metabolism to Improve Cancer-Induced Muscle Wasting.Organic and Peptidyl Constituents of Snake Venoms: The Picture Is Vastly More Complex Than We Imagined

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P2860

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

http://www.wikidata.org/entity/Q34232012

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@ast

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@en

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@nl

type

label

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@ast

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@en

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@nl

prefLabel

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@ast

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@en

SRT2104 extends survival of ma ...... preserves bone and muscle mass

@nl

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SRT2104 extends survival of ma ...... preserves bone and muscle mass

@en

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Alejandro Martin-Montalvo

http://www.w3.org/2001/XMLSchema#string

Ana P Gomes

http://www.w3.org/2001/XMLSchema#string

Christoph Westphal

http://www.w3.org/2001/XMLSchema#string

Evi M Mercken

http://www.w3.org/2001/XMLSchema#string

George P Vlasuk

http://www.w3.org/2001/XMLSchema#string

Hector H Palacios

http://www.w3.org/2001/XMLSchema#string

Husam Khraiwesh

http://www.w3.org/2001/XMLSchema#string

James L Ellis

http://www.w3.org/2001/XMLSchema#string

Jordan J Licata

http://www.w3.org/2001/XMLSchema#string

Joseph A Baur

http://www.w3.org/2001/XMLSchema#string

P2860

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

SRT1720 improves survival and healthspan of obese mice

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

PAGE: parametric analysis of gene set enrichment

P304

787-796

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scholarly article

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10.1111/ACEL.12220

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5

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13

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Morten Scheibye-Knudsen

José Antonio González-Reyes

P577

2014-06-16T00:00:00Z

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263111686

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24931715

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4172519

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