Cell type-specific gene expression in the neuroendocrine system. A neuroendocrine-specific regulatory element in the promoter of chromogranin A, a ubiquitous secretory granule core protein.
about
An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertensionBoth rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology.A functional cyclic AMP response element plays a crucial role in neuroendocrine cell type-specific expression of the secretory granule protein chromogranin A.Pancreastatin secretion by pituitary adenomas and regulation of chromogranin B mRNA expression.Analysis of the chromogranin A post-translational cleavage product pancreastatin and the prohormone convertases PC2 and PC3 in normal and neoplastic human pituitaries.Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins.Common genetic variants in the chromogranin A promoter alter autonomic activity and blood pressure.Stimulus coupling to transcription versus secretion in pheochromocytoma cells. Convergent and divergent signal transduction pathways and the crucial roles for route of cytosolic calcium entry and protein kinase C.Peptidergic activation of transcription and secretion in chromaffin cells. Cis and trans signaling determinants of pituitary adenylyl cyclase-activating polypeptide (PACAP).Secretin activation of chromogranin A gene transcription. Identification of the signaling pathways in cis and in trans.Catecholamine secretory vesicle stimulus-transcription coupling in vivo. Demonstration by a novel transgenic promoter/photoprotein reporter and inhibition of secretion and transcription by the chromogranin A fragment catestatin.Stimulus-transcription coupling in pheochromocytoma cells. Promoter region-specific activation of chromogranin a biosynthesis.Pleiotropic effects of novel trans-acting loci influencing human sympathochromaffin secretion.
P2860
Q24646356-40029992-2AAB-4E52-A8CD-CD103B9F3B93Q33909582-DBF72FA8-8108-4E1D-8725-6CC0A2F9793EQ35751316-2FCE3A3D-D9F4-49ED-A4A3-51AFA61430B8Q35773914-F9CB6DC3-4F49-4A4C-AF96-62BF051E8EF3Q35795080-FC4BB91C-CC8B-4D84-BD23-AC799ABE4B2FQ36876120-7FA1EE34-C310-4869-83ED-8355FDBCB9A9Q36957127-91C11BB6-5B72-4532-9DDE-B76CC893BF72Q37371874-6D0E7601-A334-43FE-8341-94EDA397585BQ37378273-30B1597F-FB2A-4EE9-9AF4-FECC98CCC6B0Q38356584-16BD0F78-9586-428B-9386-A37DF8FF428BQ43502817-65C59D5F-808F-47B6-A91C-27198E828DBDQ46001778-FD7D7B40-D65B-4569-BFCC-947BC8CB39ABQ46012825-98BBBD09-57ED-4530-943E-F8A24E3BA433
P2860
Cell type-specific gene expression in the neuroendocrine system. A neuroendocrine-specific regulatory element in the promoter of chromogranin A, a ubiquitous secretory granule core protein.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Cell type-specific gene expres ...... ecretory granule core protein.
@ast
Cell type-specific gene expres ...... ecretory granule core protein.
@en
Cell type-specific gene expres ...... ecretory granule core protein.
@nl
type
label
Cell type-specific gene expres ...... ecretory granule core protein.
@ast
Cell type-specific gene expres ...... ecretory granule core protein.
@en
Cell type-specific gene expres ...... ecretory granule core protein.
@nl
prefLabel
Cell type-specific gene expres ...... ecretory granule core protein.
@ast
Cell type-specific gene expres ...... ecretory granule core protein.
@en
Cell type-specific gene expres ...... ecretory granule core protein.
@nl
P2093
P2860
P356
P1476
Cell type-specific gene expres ...... ecretory granule core protein.
@en
P2093
P2860
P304
P356
10.1172/JCI117297
P407
P577
1994-07-01T00:00:00Z