Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A.
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The repetitive oligopeptide sequences modulate cytopathic potency but are not crucial for cellular uptake of Clostridium difficile toxin AClostridial glucosylating toxins enter cells via clathrin-mediated endocytosisClostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal EffectsThe Role of Rho GTPases in Toxicity of Clostridium difficile ToxinsClostridium difficile infection: molecular pathogenesis and novel therapeuticsConformational analysis of Clostridium difficile toxin B and its implications for substrate recognitionStructural Determinants of Clostridium difficile Toxin A Glucosyltransferase ActivityStructural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficileMechanism of Action and Epitopes of Clostridium difficile Toxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray CrystallographyNeutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domainBiochemical and Immunological Characterization of Truncated Fragments of the Receptor-Binding Domains of C. difficile Toxin AConventional and alternative treatment approaches for Clostridium difficile infectionStructural organization of the functional domains of Clostridium difficile toxins A and BBinding of Clostridium difficile toxins to human milk oligosaccharides.Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore.Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function.Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis.Activity of Bdellovibrio hit locus proteins, Bd0108 and Bd0109, links Type IVa pilus extrusion/retraction status to prey-independent growth signalling.Expression, purification, crystallization and preliminary crystallographic analysis of a putative Clostridium difficile surface protein Cwp19Toxin-specific antibodies for the treatment of Clostridium difficile: current status and future perspectives.Evaluation of a focused virtual library of heterobifunctional ligands for Clostridium difficile toxins.Human Clostridium difficile infection: altered mucus production and composition.Recombinant lipoprotein-based vaccine candidates against C. difficile infections.Novel Clostridium difficile Anti-Toxin (TcdA and TcdB) Humanized Monoclonal Antibodies Demonstrate In Vitro Neutralization across a Broad Spectrum of Clinical Strains and In Vivo Potency in a Hamster Spore Challenge ModelClostridium difficile toxins: mediators of inflammation.Toward a structural understanding of Clostridium difficile toxins A and B.C-terminal repeats of Clostridium difficile toxin A induce production of chemokine and adhesion molecules in endothelial cells and promote migration of leukocytesDiagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories.Clostridium difficile infection in the twenty-first century.Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells.Clostridial toxins.Variations in virulence and molecular biology among emerging strains of Clostridium difficile.Super toxins from a super bug: structure and function of Clostridium difficile toxins.The enterotoxicity of Clostridium difficile toxins.Immunization strategies for Clostridium difficile infections.Total synthesis of Le(A)-LacNAc pentasaccharide as a ligand for Clostridium difficile toxin A.Nonantimicrobial drug targets for Clostridium difficile infections.Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin.Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB.Recombinant Mucin-Type Fusion Proteins with a Galα1,3Gal Substitution as Clostridium difficile Toxin A Inhibitors.
P2860
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P2860
Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@ast
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@en
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@nl
type
label
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@ast
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@en
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@nl
prefLabel
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@ast
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@en
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@nl
P2860
P356
P1476
Crystal structure of receptor- ...... Clostridium difficile toxin A.
@en
P2093
Antonio Greco
Jason G S Ho
P2860
P304
18373-18378
P356
10.1073/PNAS.0506391102
P407
P577
2005-12-12T00:00:00Z