Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation.

Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation.

Item
http://www.wikidata.org/entity/Q34236680
Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortionIn vivo physiological and transcriptional profiling reveals host responses to Clostridium difficile toxin A and toxin BGlutamine and alanyl-glutamine increase RhoA expression and reduce Clostridium difficile toxin-a-induced intestinal epithelial cell damageCrosstalk between HDAC6 and Nox2-based NADPH oxidase mediates HIV-1 Tat-induced pro-inflammatory responses in astrocytes.Role of NADH: quinone oxidoreductase-1 in the tight junctions of colonic epithelial cells.Tubulin acetylation: responsible enzymes, biological functions and human diseases.Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis.Identification of a novel virulence factor in Clostridium difficile that modulates toxin sensitivity of cultured epithelial cells.Host-Microbiota Interactions in the Pathogenesis of Antibiotic-Associated Diseases.Clostridium difficile toxins: mediators of inflammation.Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells.The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice.Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression.Multifaceted interactions of bacterial toxins with the gastrointestinal mucosa.Photorhabdus luminescens PirAB-fusion protein exhibits both cytotoxicity and insecticidal activity.Development and evaluation of an ovine antibody-based platform for treatment of Clostridium difficile infection
P2860

Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation.

Item
http://www.wikidata.org/entity/Q34236680
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Clostridium difficile toxin A ...... s mediates acute inflammation.
@ast
Clostridium difficile toxin A ...... s mediates acute inflammation.
@en
Clostridium difficile toxin A ...... s mediates acute inflammation.
@nl
type
label
Clostridium difficile toxin A ...... s mediates acute inflammation.
@ast
Clostridium difficile toxin A ...... s mediates acute inflammation.
@en
Clostridium difficile toxin A ...... s mediates acute inflammation.
@nl
prefLabel
Clostridium difficile toxin A ...... s mediates acute inflammation.
@ast
Clostridium difficile toxin A ...... s mediates acute inflammation.
@en
Clostridium difficile toxin A ...... s mediates acute inflammation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Clostridium difficile toxin A ...... s mediates acute inflammation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932