Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes
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Fluorescent and Bioluminescent Reporter MyxovirusesDevelopment of next-generation respiratory virus vaccines through targeted modifications to viral immunomodulatory genesUtilisation of ISA Reverse Genetics and Large-Scale Random Codon Re-Encoding to Produce Attenuated Strains of Tick-Borne Encephalitis Virus within DaysEGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin ExpressionA live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuationAttenuation of tick-borne encephalitis virus using large-scale random codon re-encodingRespiratory syncytial virus, an ongoing medical dilemma: an expert commentary on respiratory syncytial virus prophylactic and therapeutic pharmaceuticals currently in clinical trialsDownregulating viral gene expression: codon usage bias manipulation for the generation of novel influenza A virus vaccines.Functional Analysis of the 60-Nucleotide Duplication in the Respiratory Syncytial Virus Buenos Aires Strain Attachment Glycoprotein.Genome-Wide Analysis of Human Metapneumovirus EvolutionRespiratory Syncytial Virus Attachment Glycoprotein Contribution to Infection Depends on the Specific Fusion Protein.Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primatesHuman respiratory syncytial virus non-structural protein NS1 modifies miR-24 expression via transforming growth factor-β.Evolutionary reversion of live viral vaccines: Can genetic engineering subdue it?A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton RatsPackaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector.Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure.Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeuticsNovel therapies and vaccines against the human respiratory syncytial virus.Attenuation of RNA viruses by redirecting their evolution in sequence space.Synthetic gene design-The rationale for codon optimization and implications for molecular pharming in plants.Identification of Respiratory Syncytial Virus Nonstructural Protein 2 Residues Essential for Exploitation of the Host Ubiquitin System and Inhibition of Innate Immune Responses.ENHANCING THE THERMOSTABILITY AND IMMUNOGENICITY OF AN RSV LIVE-ATTENUATED VACCINE BY INCORPORATING UNIQUE RSV LINE19F PROTEIN RESIDUES.Emergency Services of Viral RNAs: Repair and Remodeling.The Evolution of Molecular Compatibility between Bacteriophage ΦX174 and its Host.Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse ModelsHIV-1 Protease Evolvability Is Affected by Synonymous Nucleotide Recoding
P2860
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P2860
Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes
description
2014 nî lūn-bûn
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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Refining the balance of attenu ...... ptimization of virulence genes
@ast
Refining the balance of attenu ...... ptimization of virulence genes
@en
Refining the balance of attenu ...... ptimization of virulence genes
@nl
type
label
Refining the balance of attenu ...... ptimization of virulence genes
@ast
Refining the balance of attenu ...... ptimization of virulence genes
@en
Refining the balance of attenu ...... ptimization of virulence genes
@nl
prefLabel
Refining the balance of attenu ...... ptimization of virulence genes
@ast
Refining the balance of attenu ...... ptimization of virulence genes
@en
Refining the balance of attenu ...... ptimization of virulence genes
@nl
P2093
P2860
P356
P1433
P1476
Refining the balance of attenu ...... ptimization of virulence genes
@en
P2093
Anne L Hotard
Martin L Moore
P2860
P304
P356
10.1128/MBIO.01704-14
P577
2014-09-23T00:00:00Z