Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.
about
LRP-1: a checkpoint for the extracellular matrix proteolysisThe Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor EnvironmentEnhancement of HLA class II-restricted CD4+ T cell recognition of human melanoma cells following treatment with bryostatin-1.Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesisCleavage of Histone 3 by Cathepsin D in the involuting mammary gland.Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activitiesNew cathepsin D inhibitor library utilizing hydroxyethyl isosteres with cyclic tertiary amines.Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in micec-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis.LRP-1--CD44, a new cell surface complex regulating tumor cell adhesion.Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cellsCathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism.Two Faces of Cathepsin D: Physiological Guardian Angel and Pathological Demon.Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors.Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II.Subcellular Trafficking of Mammalian Lysosomal Proteins: An Extended View.The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells.Procathepsin d involvement in chemoresistance of cancer cells.Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2.Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans.
P2860
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P2860
Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
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Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
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Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
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Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
@ast
Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
@en
Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
@nl
prefLabel
Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
@ast
Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
@en
Pro-cathepsin D interacts with ...... ependent fibroblast outgrowth.
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P2093
P2860
P50
P356
P1476
Pro-cathepsin D interacts with ...... dependent fibroblast outgrowth
@en
P2093
Bradley T Hyman
Christine Prébois
Danielle Derocq
Gary K Smith
Hongyu Zhang
Jami Grossfield
Mélanie Beaujouin
Olivier Masson
Peter van der Geer
Robert E Hollingsworth
P2860
P304
P356
10.1242/JCS.070938
P407
P577
2010-09-07T00:00:00Z