The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.
about
Novel endogenous peptide agonists of cannabinoid receptorsThe endocannabinoid system as an emerging target of pharmacotherapyGPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M currentEndocannabinoids in the retina: from marijuana to neuroprotectionExpression and Function of the Endocannabinoid System in the Retina and the Visual BrainThe grass isn't always greener: The effects of cannabis on embryological developmentCannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A reviewForebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formationEndocannabinoid signaling in the etiology and treatment of major depressive illness.Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channelsThe K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products.Hydrophobic residues in helix 8 of cannabinoid receptor 1 are critical for structural and functional properties.Cannabinoid WIN 55,212-2 regulates TRPV1 phosphorylation in sensory neurons.Differential activation of intracellular versus plasmalemmal CB2 cannabinoid receptors.Regulatory effects of anandamide on intracellular Ca(2+) concentration increase in trigeminal ganglion neuronsPhysical and functional interaction between CB1 cannabinoid receptors and beta2-adrenoceptorsType 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons.Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1).Ligand Binding Sensitivity of the Extracellular Loop Two of the Cannabinoid Receptor 1.Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.Exploring a role for heteromerization in GPCR signalling specificity.The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide.An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction.4'-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation.The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons.Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptorAspects of endocannabinoid signaling in periimplantation biologyWhat is the role of astrocyte calcium in neurophysiology?Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent.Differential modulation of AP-1- and CRE-driven transcription by cannabinoid agonists emphasizes functional selectivity at the CB1 receptor.Regulation of female fertility by the endocannabinoid system.Time-dependent induction of CREB phosphorylation in the hippocampus by the endogenous cannabinoid.Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action.CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release.Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neuronsConstitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists.Endocannabinoid-mediated control of synaptic transmission.
P2860
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P2860
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@ast
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@en
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@nl
type
label
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@ast
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@en
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@nl
prefLabel
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@ast
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@en
The cannabinoid agonist WIN55, ...... coupling to Gq/11 G proteins.
@nl
P2860
P921
P356
P1476
The cannabinoid agonist WIN55, ...... r coupling to Gq/11 G proteins
@en
P2093
Bertil Hille
Jane E Lauckner
P2860
P304
19144-19149
P356
10.1073/PNAS.0509588102
P407
P50
P577
2005-12-19T00:00:00Z