Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.
about
Novel immunotherapeutic approaches for the treatment of acute leukemia (myeloid and lymphoblastic)Advances in graft-versus-host disease biology and therapy.OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection.Immunological considerations in in utero hematopoetic stem cell transplantation (IUHCT)Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution.Mechanisms of antigen presentation to T cells in murine graft-versus-host disease: cross-presentation and the appearance of cross-presentation.Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation.Memory T cells and their exhaustive differentiation in allograft tolerance and rejection.Allospecific CD4(+) effector memory T cells do not induce graft-versus-host disease in mice.Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.Allogeneic T cell responses are regulated by a specific miRNA-mRNA network.Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease.Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T Cells.Emerging concepts in haematopoietic cell transplantation.Immunomodulatory Drugs: Immune Checkpoint Agents in Acute Leukemia.Sensitization of human osteosarcoma cells to Vγ9Vδ2 T-cell-mediated cytotoxicity by zoledronate.Langerhans cells regulate cutaneous injury by licensing CD8 effector cells recruited to the skinPD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells.Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers.Peripheral tissues reprogram CD8+ T cells for pathogenicity during graft-versus-host disease.Unique features and clinical importance of acute alloreactive immune responses.
P2860
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P2860
Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@ast
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@en
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@nl
type
label
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@ast
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@en
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@nl
prefLabel
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@ast
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@en
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@nl
P2093
P2860
P50
P356
P1476
Nonhematopoietic antigen block ...... f bone marrow transplantation.
@en
P2093
Barry Flutter
Farnaz Fallah-Arani
Gordon J Freeman
Jian-Guo Chai
Megan Sykes
Noha Edwards
Sara Ghorashian
Shivajanani Sivakumaran
P2860
P304
P356
10.1172/JCI41446
P407
P577
2010-10-18T00:00:00Z