MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors.
about
Clinical application of adoptive T cell therapy in solid tumorsEngineered T cells for cancer treatmentCytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma.CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptorTargeting c-MYC with T-cellsCodon optimization of the human papillomavirus E7 oncogene induces a CD8+ T cell response to a cryptic epitope not harbored by wild-type E7Survivin-specific T cell receptor targets tumor but not T cells.Serum HMGB1 is a predictive and prognostic biomarker for oncolytic immunotherapy.T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cellsThymic expression of a T-cell receptor targeting a tumor-associated antigen coexpressed in the thymus induces T-ALLCancer-testis antigen cyclin A1 is broadly expressed in ovarian cancer and is associated with prolonged time to tumor progression after platinum-based therapy.Immunotherapy targets in pediatric cancer.A T-cell-directed chimeric antigen receptor for the selective treatment of T-cell malignanciesGeneration of CD20-specific TCRs for TCR gene therapy of CD20low B-cell malignancies insusceptible to CD20-targeting antibodies.Is it time to abandon RHAMM/HMMR as a candidate antigen for immunotherapy of acute myeloid leukemia?RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia.Limitations for TCR gene therapy by MHC-restricted fratricide and TCR-mediated hematopoietic stem cell toxicity.Augmentation of anti-tumor immunity by adoptive T-cell transfer after allogeneic hematopoietic stem cell transplantation.Can immunotherapy specifically target acute myeloid leukemic stem cells?Chimeric NKG2D CAR-expressing T cell-mediated attack of human ovarian cancer is enhanced by histone deacetylase inhibition.Fratricide of natural killer cells dressed with tumor-derived NKG2D ligand.Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLAAlloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes.Is cancer gene therapy an empty suit?Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8+ T cells directed against tumor-associated antigens.Challenges in T cell receptor gene therapy.Leukemia-associated antigens and their relevance to the immunotherapy of acute myeloid leukemia.Peptide-based vaccination and induction of CD8+ T-cell responses against tumor antigens in breast cancer.Tools to define the melanoma-associated immunopeptidome.Antigen processing and immune regulation in the response to tumours.Immunomodulatory monoclonal antibodies combined with peptide vaccination provide potent immunotherapy in an aggressive murine neuroblastoma model.NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability.Increased PRAME antigen-specific killing of malignant cell lines by low avidity CTL clones, following treatment with 5-Aza-2'-Deoxycytidine.Exploring dendritic cell based vaccines targeting survivin for the treatment of head and neck cancer patients.Characterization of T-cell responses against IκBα in cancer patients.Dendritic cell vaccines targeting survivin in head and neck cancer.A Dynamic Model of Immune Responses to Antigen Presentation Predicts Different Regions of Tumor or Pathogen Elimination.Treating hematological malignancies with cell therapy: where are we now?Systematic identification of cancer-specific MHC-binding peptides with RAVEN
P2860
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P2860
MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@ast
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@en
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@nl
type
label
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@ast
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@en
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@nl
prefLabel
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@ast
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@en
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@nl
P2093
P2860
P356
P1476
MHC-restricted fratricide of h ...... c transgenic T cell receptors.
@en
P2093
Bernhard Frankenberger
Dolores J Schendel
Matthias Leisegang
Slavoljub Milosevic
Stefani Spranger
Susanne Wilde
Wolfgang Uckert
P2860
P304
P356
10.1172/JCI43437
P407
P577
2010-10-11T00:00:00Z