hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing
about
Splicing Regulation: A Molecular Device to Enhance Cancer Cell AdaptationPhosphorylation-mediated regulation of alternative splicing in cancerLarge-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networksA natural-like synthetic small molecule impairs bcr-abl signaling cascades and induces megakaryocyte differentiation in erythroleukemia cellsCaspase-9: structure, mechanisms and clinical applicationLiving or dying by RNA processing: caspase expression in NSCLC.Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer.Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a.SRSF1 regulates the alternative splicing of caspase 9 via a novel intronic splicing enhancer affecting the chemotherapeutic sensitivity of non-small cell lung cancer cellsAlternative RNA splicing and cancerCeramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme.Regulation of chemoresistance via alternative messenger RNA splicingEffects of oxygen on the antigenic landscape of prostate cancer cells.The Proto-oncogene PKCι regulates the alternative splicing of Bcl-x pre-mRNA.The Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer.Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression.hnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP LCaspase-9b Interacts Directly with cIAP1 to Drive Agonist-Independent Activation of NF-κB and Lung TumorigenesisOncogenic alternative splicing switches: role in cancer progression and prospects for therapy.HnRNP L is important for the expression of oncogene SRSF3 and oncogenic potential of oral squamous cell carcinoma cells.Long noncoding RNA uc.345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression.HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells.Modulation of alternative splicing by anticancer drugs.Crosslinking-immunoprecipitation (iCLIP) analysis reveals global regulatory roles of hnRNP L.The apoptotic and genomic studies on A549 cell line induced by silver nitrate.Antineoplastic effects of 15(S)-hydroxyeicosatetraenoic acid and 13-S-hydroxyoctadecadienoic acid in non-small cell lung cancer.Alternative splicing and cell survival: from tissue homeostasis to disease.HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA.Alternative splicing networks regulated by signaling in human T cells.An integrative framework identifies alternative splicing events in colorectal cancer development.Interplay between miR-574-3p and hnRNP L regulates VEGFA mRNA translation and tumorigenesis.Akt Signaling Is Sustained by a CD44 Splice Isoform-Mediated Positive Feedback Loop.AR-A 014418 Used against GSK3beta Downregulates Expression of hnRNPA1 and SF2/ASF Splicing Factors.HnRNP-L promotes prostate cancer progression by enhancing cell cycling and inhibiting apoptosis.Splice variants of cytosolic polyadenylation element-binding protein 2 (CPEB2) differentially regulate pathways linked to cancer metastasis.Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer.Environmental perturbations lead to extensive directional shifts in RNA processing.Presenilin Mutation Suppresses Lung Tumorigenesis via Inhibition of Peroxiredoxin 6 Activity and Expression.
P2860
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P2860
hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@ast
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@en
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@nl
type
label
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@ast
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@en
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@nl
prefLabel
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@ast
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@en
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@nl
P2093
P2860
P356
P1476
hnRNP L regulates the tumorige ...... caspase-9 pre-mRNA processing
@en
P2093
Charles E Chalfant
Charuta Murudkar
D Ross Camidge
Davis H Massey
Jacqueline C Shultz
Jerry W Shay
John D Minna
Lian Zhang
Nadia F Lamour
Rachel Wilson Goehe
P2860
P304
P356
10.1172/JCI43552
P407
P577
2010-10-25T00:00:00Z