Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization.
about
miRNA response to DNA damageThe microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner.RETRACTED: Nuclear Extracellular Signal-Regulated Kinase 1 and 2 Translocation Is Mediated by Casein Kinase 2 and Accelerated by AutophosphorylationCytoplasmic Drosha activity generated by alternative splicingAPC/C-mediated degradation of dsRNA-binding protein 4 (DRB4) involved in RNA silencingA novel role for GSK3β as a modulator of Drosha microprocessor activity and MicroRNA biogenesisDrosha as an interferon-independent antiviral factor.Glycogen synthase kinase 3 beta (GSK3β) phosphorylates the RNAase III enzyme Drosha at S300 and S302Acetylation of drosha on the N-terminus inhibits its degradation by ubiquitination.GSK3 inhibitors CHIR99021 and 6-bromoindirubin-3'-oxime inhibit microRNA maturation in mouse embryonic stem cellsEvidence for a cytoplasmic microprocessor of pri-miRNAsSUMOylation of TARBP2 regulates miRNA/siRNA efficiency.Evolutionary dynamics of gene and isoform regulation in Mammalian tissues.Cytoplasmic RNA viruses as potential vehicles for the delivery of therapeutic small RNAs.Proteomics for understanding miRNA biology.Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile.Dysregulation of microRNA biogenesis machinery in cancer.Glycogen synthase kinase 3 beta inhibits microRNA-183-96-182 cluster via the β-Catenin/TCF/LEF-1 pathway in gastric cancer cells.MicroRNAs and DNA damage response: implications for cancer therapy.Processing of virus-derived cytoplasmic primary-microRNAs.RACK1 and the microRNA pathway: is it déjà-vu all over again?Dysregulation of microRNA biogenesis and gene silencing in cancer.IKKα-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.Non-coding RNAs: An Introduction.RNase III nucleases from diverse kingdoms serve as antiviral effectors.S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells.Alternative splicing affects the subcellular localization of Drosha.Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells.Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901.DROSHA targets its own transcript to modulate alternative splicing.Pyk2 cytonuclear localization: mechanisms and regulation by serine dephosphorylation.A genetic screen to discover SUMOylated proteins in living mammalian cells.Emerging roles of DROSHA beyond primary microRNA processing.TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β.Exosomal Tat protein activates latent HIV-1 in primary, resting CD4+ T lymphocytes.Expression of the microRNA regulators Drosha, Dicer and Ago2 in non-small cell lung carcinomas.Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas.Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during development
P2860
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P2860
Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Phosphorylation of the RNase I ...... for its nuclear localization.
@ast
Phosphorylation of the RNase I ...... for its nuclear localization.
@en
Phosphorylation of the RNase I ...... for its nuclear localization.
@nl
type
label
Phosphorylation of the RNase I ...... for its nuclear localization.
@ast
Phosphorylation of the RNase I ...... for its nuclear localization.
@en
Phosphorylation of the RNase I ...... for its nuclear localization.
@nl
prefLabel
Phosphorylation of the RNase I ...... for its nuclear localization.
@ast
Phosphorylation of the RNase I ...... for its nuclear localization.
@en
Phosphorylation of the RNase I ...... for its nuclear localization.
@nl
P2093
P2860
P356
P1476
Phosphorylation of the RNase I ...... for its nuclear localization.
@en
P2093
Bharat Ramratnam
Lynne Tucker
Xiaoli Tang
Yingjie Zhang
P2860
P304
P356
10.1093/NAR/GKQ547
P407
P577
2010-06-16T00:00:00Z