The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone - Wikidata - wikimedia - TriplyDB

The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone

The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone

http://www.wikidata.org/entity/Q34251106

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Guidelines for the use and interpretation of assays for monitoring autophagy Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?Treatment Strategies that Enhance the Efficacy and Selectivity of Mitochondria-Targeted Anticancer Agents Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model ROS homeostasis and metabolism: a dangerous liason in cancer cells A mitochondrial-targeted coenzyme q analog prevents weight gain and ameliorates hepatic dysfunction in high-fat-fed mice Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases Basic principles and emerging concepts in the redox control of transcription factors Cytoprotection "gone astray": Nrf2 and its role in cancer Nrf2 protects mitochondrial decay by oxidative stress Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis Mitochondrial-targeted curcuminoids: a strategy to enhance bioavailability and anticancer efficacy of curcumin Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.Activating Nrf-2 signaling depresses unilateral ureteral obstruction-evoked mitochondrial stress-related autophagy, apoptosis and pyroptosis in kidney.DAP1, a negative regulator of autophagy, controls SubAB-mediated apoptosis and autophagy.Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells Nrf2 enhances myocardial clearance of toxic ubiquitinated proteins Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity The Hedgehog signalling pathway regulates autophagy.Antioxidant and cytoprotective effects of L-Serine on human endothelial cells.Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels.Iron chelators with topoisomerase-inhibitory activity and their anticancer applications.Mitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo.Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death.Understanding the role of NRF2-regulated miRNAs in human malignancies.tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation.Mechanisms of hepatic fibrogenesis.Cellular metabolic and autophagic pathways: traffic control by redox signaling.Regulation of autophagy by amino acids and MTOR-dependent signal transduction.Nuclear factor erythroid-2 related factor 2 (Nrf2)-mediated protein quality control in cardiomyocytes.Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies.Linkage of E2F1 transcriptional network and cell proliferation with respiratory chain activity in breast cancer cells.Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation.

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The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone

http://www.wikidata.org/entity/Q34251106

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The antioxidant transcription ...... cancer redox agent mitoquinone

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The antioxidant transcription ...... cancer redox agent mitoquinone

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The antioxidant transcription ...... cancer redox agent mitoquinone

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type

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The antioxidant transcription ...... cancer redox agent mitoquinone

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The antioxidant transcription ...... cancer redox agent mitoquinone

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The antioxidant transcription ...... cancer redox agent mitoquinone

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The antioxidant transcription ...... cancer redox agent mitoquinone

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The antioxidant transcription ...... cancer redox agent mitoquinone

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The antioxidant transcription ...... cancer redox agent mitoquinone

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Journal of Biological Chemistry

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The antioxidant transcription ...... cancer redox agent mitoquinone

@en

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Balaraman Kalyanaraman

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Emily Shacter

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Jacek Zielonka

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Jennifer S Dickey

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Joy Joseph

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Naoko Mizuno

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Paul W Keller

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Sarah R Klein

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Spencer J Bonar

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V Ashutosh Rao

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

Selective degradation of mitochondria by mitophagy

Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16

NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics

Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds

How to interpret LC3 immunoblotting

On respiratory impairment in cancer cells

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