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Reversal of behavioral deficits and synaptic dysfunction in mice overexpressing neuregulin 1

Reversal of behavioral deficits and synaptic dysfunction in mice overexpressing neuregulin 1

http://www.wikidata.org/entity/Q34251681

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Neuropathologic implication of peripheral neuregulin-1 and EGF signals in dopaminergic dysfunction and behavioral deficits relevant to schizophrenia: their target cells and time window Neuronal migration abnormalities and its possible implications for schizophrenia Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model.ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination.Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease Activity-dependent adaptations in inhibitory axons Transmembrane protein 108 is required for glutamatergic transmission in dentate gyrus Neuregulin 1 Prevents Phencyclidine-Induced Behavioral Impairments and Disruptions to GABAergic Signaling in Mice Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model.Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice.S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model.Neurobehavioral Differences Between Mice Receiving Distinct Neuregulin Variants as Neonates; Impact on Sensitivity to MK-801.Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models.Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2 Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice Genetic labeling reveals novel cellular targets of schizophrenia susceptibility gene: distribution of GABA and non-GABA ErbB4-positive cells in adult mouse brain.Transient overexposure of neuregulin 3 during early postnatal development impacts selective behaviors in adulthood.Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons.VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function.Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex.Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.Neuregulin-1 attenuates cognitive function impairments in a transgenic mouse model of Alzheimer's disease.Lrp4 in astrocytes modulates glutamatergic transmission Neuregulin-1 impairs the long-term depression of hippocampal inhibitory synapses by facilitating the degradation of endocannabinoid 2-AG Regulation of spine formation by ErbB4 in PV-positive interneurons.Reversible overexpression of bace1-cleaved neuregulin-1 N-terminal fragment induces schizophrenia-like phenotypes in mice Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases Altering the course of schizophrenia: progress and perspectives.LIM kinases: cofilin and beyond.Do individually ventilated cage systems generate a problem for genetic mouse model research?Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex.A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia.Spironolactone is an antagonist of NRG1-ERBB4 signaling and schizophrenia-relevant endophenotypes in mice Overexpression of Neuregulin 1 Type III Confers Hippocampal mRNA Alterations and Schizophrenia-Like Behaviors in Mice.Calcyon stimulates neuregulin 1 maturation and signaling.Down-Regulation of Neuregulin1/ErbB4 Signaling in the Hippocampus Is Critical for Learning and Memory.

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P2860

Reversal of behavioral deficits and synaptic dysfunction in mice overexpressing neuregulin 1

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2013 nî lūn-bûn

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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2013 թվականի մայիսին հրատարակված գիտական հոդված

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2013年の論文

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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J.NEURON.2013.03.028

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Reversal of behavioral deficit ...... ce overexpressing neuregulin 1

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Anupama Sathyamurthy

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Chengyong Shen

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Clifford A Smith

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Dong-Min Yin

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Lin Mei

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Thiri W Lin

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Wen-Cheng Xiong

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Xihui Liu

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Yi-Sheng Lu

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Yong-Jun Chen

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P2860

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease

Association of neuregulin 1 with schizophrenia confirmed in a Scottish population

Common variants conferring risk of schizophrenia

Neuregulin 1 and susceptibility to schizophrenia.

Specific regulation of NRG1 isoform expression by neuronal activity

Common variants on chromosome 6p22.1 are associated with schizophrenia

Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system

A decrease of reelin expression as a putative vulnerability factor in schizophrenia

Phenotypic characterization of transgenic mice overexpressing neuregulin-1

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Jonathan C Bean

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