Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase.
about
Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIαThe crystal structure of the phosphatidylinositol 4-kinase IIαDeciphering the roles of phosphoinositide lipids in phagolysosome biogenesisPhosphoinositides: tiny lipids with giant impact on cell regulationRab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphateArf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism.The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor designDesign and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβThe relationship between glucocerebrosidase mutations and Parkinson diseaseACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein bindingCinderella story: PI4P goes from precursor to key signaling moleculeType II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in DrosophilaThe lipid kinase PI4KIIIβ preserves lysosomal identityA novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi.Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis.Endosomal sorting of VAMP3 is regulated by PI4K2A.The pallidopyramidal syndromes: nosology, aetiology and pathogenesis.Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis.GABARAPs regulate PI4P-dependent autophagosome:lysosome fusion.Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype.Phosphatidylinositol 4-kinases and PI4P metabolism in the nervous system: roles in psychiatric and neurological diseases.Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks.Phosphatidylinositol-4-phosphate: the Golgi and beyond.Genetic convergence of Parkinson's disease and lysosomal storage disorders.Mannose 6-phosphate-independent Lysosomal Sorting of LIMP-2.HLA-B27 Correlates with the Intracellular Elimination, Replication, and Trafficking of Salmonella Enteritidis Collected from Reactive Arthritis Patients.Phosphoinositide Diversity, Distribution, and Effector Function: Stepping Out of the Box.The Many Roles of Type II Phosphatidylinositol 4-Kinases in Membrane Trafficking: New Tricks for Old Dogs.The role of S-acylation in protein trafficking.PI4KIIα phosphorylation by GSK3 directs vesicular trafficking to lysosomes.SAC1 degrades its lipid substrate PtdIns4P in the endoplasmic reticulum to maintain a steep chemical gradient with donor membranes.Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease.PI4KIIα regulates insulin secretion and glucose homeostasis via a PKD-dependent pathway.
P2860
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P2860
Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@ast
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@en
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@nl
type
label
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@ast
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@en
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@nl
prefLabel
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@ast
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@en
Two phosphatidylinositol 4-kin ...... enzyme, β-glucocerebrosidase.
@nl
P2093
P2860
P50
P356
P1476
Two phosphatidylinositol 4-kin ...... e enzyme, β-glucocerebrosidase
@en
P2093
Gordon Polevoy
Marko Jović
Michelle J Kean
Zsofia Szentpetery
P2860
P304
P356
10.1091/MBC.E11-06-0553
P577
2012-02-15T00:00:00Z