cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane
about
Role of EPAC in cAMP-Mediated Actions in Adrenocortical CellsExchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeuticsRap1 Spatially Controls ArhGAP29 To Inhibit Rho Signaling during Endothelial Barrier Regulation.Biophysical and molecular-dynamics studies of phosphatidic acid binding by the Dvl-2 DEP domain.[EXPRESS] Epac and Nociceptor Sensitization.Allosteric inhibition of Epac: computational modeling and experimental validation to identify allosteric sites and inhibitorsThe future of EPAC-targeted therapies: agonism versus antagonismA putative novel protein, DEPDC1B, is overexpressed in oral cancer patients, and enhanced anchorage-independent growth in oral cancer cells that is mediated by Rac1 and ERK.Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1.Identification and validation of modulators of exchange protein activated by cAMP (Epac) activity: structure-function implications for Epac activation and inhibition.An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer.Latest developments in experimental and computational approaches to characterize protein-lipid interactions.The Molecules of Sperm Exocytosis.The role of Epac in the heart.Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities.An Orally Active Epac Inhibitor Reverses Mechanical Allodynia and Loss of Intraepidermal Nerve Fibers \iIn A Mouse Model of Chemotherapy-Induced Peripheral Neuropathy.The PDE4 cAMP-Specific Phosphodiesterases: Targets for Drugs with Antidepressant and Memory-Enhancing Action.Spatial control of Epac2 activity by cAMP and Ca2+-mediated activation of Ras in pancreatic β cells.Phosphatidic acid induces decidualization by stimulating Akt-PP2A binding in human endometrial stromal cells.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Using cAMP Sensors to Study Cardiac Nanodomains.
P2860
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P2860
cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@ast
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@en
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@nl
type
label
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@ast
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@en
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@nl
prefLabel
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@ast
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@en
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@nl
P2093
P2860
P356
P1476
cAMP regulates DEP domain-medi ...... ic acid at the plasma membrane
@en
P2093
Emma Spanjaard
Johannes L Bos
Martijn Gloerich
Sarah V Consonni
P2860
P304
P356
10.1073/PNAS.1117599109
P407
P577
2012-02-16T00:00:00Z