Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery. - Wikidata - wikimedia - TriplyDB

Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery.

Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery.

http://www.wikidata.org/entity/Q34264835

about

A human-curated annotation of the Candida albicans genome.Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes Predicting Essential Genes and Proteins Based on Machine Learning and Network Topological Features: A Comprehensive Review Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events Validation of the tetracycline regulatable gene expression system for the study of the pathogenesis of infectious disease De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans Recent advances on Candida albicans biology and virulence Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis Essential gene identification and drug target prioritization in Aspergillus fumigatus Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes Rechecking the Centrality-Lethality Rule in the Scope of Protein Subcellular Localization Interaction Networks Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress A New Method for Identifying Essential Proteins Based on Network Topology Properties and Protein Complexes Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis Selective BET bromodomain inhibition as an antifungal therapeutic strategy Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis.Conserved fungal genes as potential targets for broad-spectrum antifungal drug discovery.Towards the identification of essential genes using targeted genome sequencing and comparative analysis.Signature-tagged mutagenesis: barcoding mutants for genome-wide screens.Towards the prediction of essential genes by integration of network topology, cellular localization and biological process information.Evolutionary tinkering with conserved components of a transcriptional regulatory network.Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity.CEG: a database of essential gene clusters.The transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatus Molecular genetic techniques for gene manipulation in Candida albicans.Comparative genomics allowed the identification of drug targets against human fungal pathogens.Role for the SCFCDC4 ubiquitin ligase in Candida albicans morphogenesis Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans Genetic basis of Candida biofilm resistance due to drug-sequestering matrix glucan.Functional genomic analysis of the rates of protein evolution.Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy Training set selection for the prediction of essential genes Role of Fks1p and matrix glucan in Candida albicans biofilm resistance to an echinocandin, pyrimidine, and polyene An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms.Compound prioritization methods increase rates of chemical probe discovery in model organisms.Antifungal drug discovery: the process and outcomes.A new essential protein discovery method based on the integration of protein-protein interaction and gene expression data.

P2860

Q21145286-F2C31D85-E5B1-476E-B3E4-C3E6153AFE59 Q21267230-4DFB57BE-03BC-461B-9FDC-83E1CFF04DB1 Q26751128-59FC9BC5-7859-43F2-A9E2-907E467CB0B8 Q27332296-BCF233D5-7440-4CA2-8623-4F3A0EC2D4EB Q27338028-4C956C61-14BB-45C5-9FEF-50F9420C6550 Q27674590-881E7875-1359-4068-BF81-4FCA81C270E8 Q28066567-BC7EBC3E-8319-46B4-A7C8-BC81E3077F2B Q28469010-0FF74FD5-C03F-4020-A822-DF0104758E7C Q28469156-8BAC0C3C-5ABA-4012-939B-DE1813E3AB62 Q28469241-94AD7092-F728-4EDC-B603-0D6AD68A7EFB Q28475711-F0F24906-E615-46EA-98C8-32570DF0AF2A Q28539874-16C05CCB-2C2F-4271-B2D4-A3C9C3FECC46 Q28545822-839150FD-8779-40B3-999F-CDA1686D4496 Q28552131-32132F8D-3A2B-4056-BF8F-A3FACA4D29C2 Q28553550-8059E962-823F-44AC-A714-48C170D19105 Q28554456-60F80C6D-B870-4BAC-AEDE-A30FCBA5292F Q30354737-4464E567-6F76-4F53-90B9-B3E5C389599A Q30583463-998CF470-1198-4508-8EC5-4148CFC53753 Q33239546-57FDEB65-1474-40EA-8407-5B26F0FF509E Q33260930-7059700A-301B-49A5-83C5-F369368BB394 Q33265184-1AC330D9-7592-4A99-AB52-960F01C36E40 Q33503874-3E958EB3-DE1D-4391-A034-0E9504F49D64 Q33540999-9B03CD57-511F-4F05-944D-7D4BD8A03E1B Q33579032-552B69D7-2668-4068-8767-D81EC51B9E37 Q33602928-6CB4A67C-84BB-4AB3-828E-C397363ECCEC Q33715691-7198A509-0AE3-4389-BD56-B88456EC4EDF Q33725213-057DC91F-FDF0-483D-8027-C20068166792 Q33779105-CC3076B8-7866-4ABC-9892-B52E7B64BB97 Q33805404-AF715D01-14D6-4ED6-AEA0-76A917CA1FDA Q33841398-1C7FE4E7-FF96-42F4-8FC2-D976A85FC989 Q33859372-3F64A93F-FF91-49C6-A516-AA9A10B9ADF5 Q33893698-3A853E2B-4359-4757-8170-7662B14C9EEA Q33935339-A897D296-8E8B-4EF3-A7E7-655F1B070AD4 Q33940382-9BF00E94-CCCB-47D4-B4F4-B0252C6F420F Q34039685-D548E6DB-1AF9-4CCD-9E76-226AB29AA41F Q34045325-71BD7A96-3A38-4FB7-A63E-EE1426E3EFCD Q34047417-D8E398E5-9C31-41E2-8868-0092FAD2AF65 Q34061093-B2C0A34D-65C9-43ED-87F3-4DD87ECE520D Q34086897-35DF7A63-0D2B-408B-B89C-A0AA375BB539 Q34190287-DB244C5D-5710-40D0-AA63-4CE7E12CD253

P2860

Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery.

http://www.wikidata.org/entity/Q34264835

description

2003 nî lūn-bûn

@nan

2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Large-scale essential gene ide ...... to antifungal drug discovery.

@ast

Large-scale essential gene ide ...... to antifungal drug discovery.

@en

Large-scale essential gene ide ...... to antifungal drug discovery.

@nl

type

label

Large-scale essential gene ide ...... to antifungal drug discovery.

@ast

Large-scale essential gene ide ...... to antifungal drug discovery.

@en

Large-scale essential gene ide ...... to antifungal drug discovery.

@nl

prefLabel

Large-scale essential gene ide ...... to antifungal drug discovery.

@ast

Large-scale essential gene ide ...... to antifungal drug discovery.

@en

Large-scale essential gene ide ...... to antifungal drug discovery.

@nl

P1433

Q34264835-478E5ACB-1EB0-4464-A3D7-6033D3271AD1

P1476

Q34264835-BCE2BE6D-33ED-48CF-AA0B-089BE7B60A5F

P2093

Q34264835-10B5E6B1-FB30-48D9-83E4-D4536C6B44D9

Q34264835-2005C73E-10FD-42AA-94C8-98A7809CDCCB

Q34264835-205BECF3-CE4D-457E-969C-D98B9B69AF57

Q34264835-453DCD31-8F69-441E-8FDB-8F532B43FB66

Q34264835-4A713660-8135-417C-A433-49F0383FA9B8

Q34264835-57B49EF3-0C0B-4460-8E37-95337B712566

Q34264835-65C89446-22BD-403B-80B3-4132775ACC13

Q34264835-69BE4F9A-D1B5-4966-B791-FA3B2CB09B00

Q34264835-6F44F182-80AA-4358-8985-E386D9801174

Q34264835-7C2B60EA-92E7-49E9-A710-CF79E4D360F7

P2860

Q34264835-209030AC-611B-4B5F-B142-2FE648E660AC

Q34264835-56BFB58B-3185-43F0-9FC4-6752551CB7D3

Q34264835-BEE2898E-974D-4033-B572-B5CDA937D17A

P304

Q34264835-5D6D14F8-3957-480D-A269-C6721C775C4A

P31

Q34264835-563508D7-3ACF-4C8A-96D2-6E87A6D09346

P356

Q34264835-8CC123C8-5B29-4BBF-831E-1EF9623B4E6B

P407

Q34264835-46EE6DC0-5EDD-4895-AAA9-283F79FE9FEB

P433

Q34264835-A506ADFC-C9D0-4C49-86A5-43CD5CB7F0F4

P478

Q34264835-978238DF-5B77-475E-841A-6C6B1DF65227

P50

Q34264835-4C023E05-CE61-4092-8C35-682F48740942

Q34264835-7EC68B1B-97B1-466B-9EEE-0ED94B2A74DA

P577

Q34264835-A5706A03-3F14-4007-8AF5-FF1761F89577

P5875

Q34264835-B9060414-3FCD-4215-9495-CC2CF478A283

P698

Q34264835-21CB04ED-DDDB-4054-8744-5A56E5AEC25D

P356

J.1365-2958.2003.03697.X

P1433

Molecular Microbiology

P1476

Large-scale essential gene ide ...... to antifungal drug discovery.

@en

P2093

Annie Linteau

http://www.w3.org/2001/XMLSchema#string

Anouk Breton

http://www.w3.org/2001/XMLSchema#string

Bo Jiang

http://www.w3.org/2001/XMLSchema#string

Catarina Marta

http://www.w3.org/2001/XMLSchema#string

Charles Boone

http://www.w3.org/2001/XMLSchema#string

Fatou Tandia

http://www.w3.org/2001/XMLSchema#string

Howard Bussey

http://www.w3.org/2001/XMLSchema#string

Jeff Becker

http://www.w3.org/2001/XMLSchema#string

John Davison

http://www.w3.org/2001/XMLSchema#string

Karynn Veillette

http://www.w3.org/2001/XMLSchema#string

P2860

Basic local alignment search tool

Chromosomal alterations of Candida albicans are associated with the gain and loss of assimilating functions.

Isolation of the Candida albicans homologs of Saccharomyces cerevisiae KRE6 and SKN1: expression and physiological function.

P304

167-181

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1046/J.1365-2958.2003.03697.X

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

50

http://www.w3.org/2001/XMLSchema#string

P50

Sébastien Lemieux

P577

2003-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

9083078

http://www.w3.org/2001/XMLSchema#string

P698

14507372

http://www.w3.org/2001/XMLSchema#string