Tibolone: a steroid with a tissue-specific mode of action.
about
Comparative effects of conventional hormone replacement therapy and tibolone on climacteric symptoms and sexual dysfunction in postmenopausal womenTibolone: the way to beat many a postmenopausal ailmentsDetermination of 3-α-hydroxytibolone in human plasma by LC-MS/MS: application for a pharmacokinetic study after administration of a tibolone formulation.Tibolone modulates neuronal plasticity through regulating Tau, GSK3β/Akt/PI3K pathway and CDK5 p35/p25 complexes in the hippocampus of aged male mice.Metabolism of the synthetic progestogen norethynodrel by human ketosteroid reductases of the aldo-keto reductase superfamilyIn vivo and in vitro estrogenic and progestagenic actions of Tibolone.What is tibolone--and is it a SPEAR?Pharmacotherapy of osteoporosis in postmenopausal women: focus on safety.Distribution of cyclooxygenases 1 and 2 in the uterus and breast of cynomolgus monkeys-effects of hormone treatment.Promiscuity and diversity in 3-ketosteroid reductases.Tibolone: a unique version of hormone replacement therapy.Pharmacokinetics of tibolone in early and late postmenopausal women.Effects of oestrogen receptor-active compounds on lipid metabolism.The need for tissue selective menopausal agents.Loss of libido in postmenopausal women.Tibolone and breast cancer.Risk factors, pathophysiology, and treatment of hot flashes in cancer.Cardiovascular effects of tibolone: a selective tissue estrogenic activity regulator.Endometrial safety and bleeding with HRT: what's new?Soy-tibolone combination - effect on lipids in postmenopausal monkeys and women.Molecular analysis of human endometrium: short-term tibolone signaling differs significantly from estrogen and estrogen + progestagen signaling.Testosterone replacement therapy in the climacteric: benefits beyond sexuality.What can be done about hot flushes after treatment for breast cancer?Drugs for the treatment of menopausal symptoms.Tibolone Preserves Mitochondrial Functionality and Cell Morphology in Astrocytic Cells Treated with Palmitic Acid.Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat.Dose-response analysis of effects of tibolone on climacteric symptoms.Bioequivalence studies of tibolone in premenopausal women and effects on expression of the tibolone-metabolizing enzyme AKR1C (aldo-keto reductase) family caused by estradiol.Effects of tibolone on sulfatase pathway of estrogens metabolism and on growth of MCF-7 human breast tumors implanted in ovariectomized nude mice.Interactions of the human cytosolic sulfotransferases and steroid sulfatase in the metabolism of tibolone and raloxifene.Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism.Evaluation of tibolone effect on arterial resistance in postmenopausal women.Effects of transdermal estradiol gel and oral tibolone on health-related quality of life after surgical menopause.Tibolone lowers high density lipoprotein cholesterol by increasing hepatic lipase activity but does not impair cholesterol efflux.Ten years of treatment with tibolone 2.5 mg daily: effects on bone loss in postmenopausal women.Acute effects of tibolone on cerebral vascular reactivity in vitro.Effects of tibolone or continuous combined oestradiol/norethisterone acetate on glucose and insulin metabolism.The effect of tibolone in postmenopausal women receiving tamoxifen after surgery for breast cancer: a randomised, double-blind, placebo-controlled trial.Long-term effects of tibolone on the endometrium as assessed by bleeding episodes, transvaginal scan and endometrial biopsy.Dissolution rate enhancement of the poorly water-soluble drug Tibolone using PVP, SiO2, and their nanocomposites as appropriate drug carriers.
P2860
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P2860
Tibolone: a steroid with a tissue-specific mode of action.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Tibolone: a steroid with a tissue-specific mode of action.
@ast
Tibolone: a steroid with a tissue-specific mode of action.
@en
Tibolone: a steroid with a tissue-specific mode of action.
@nl
type
label
Tibolone: a steroid with a tissue-specific mode of action.
@ast
Tibolone: a steroid with a tissue-specific mode of action.
@en
Tibolone: a steroid with a tissue-specific mode of action.
@nl
prefLabel
Tibolone: a steroid with a tissue-specific mode of action.
@ast
Tibolone: a steroid with a tissue-specific mode of action.
@en
Tibolone: a steroid with a tissue-specific mode of action.
@nl
P1476
Tibolone: a steroid with a tissue-specific mode of action.
@en
P2093
Kloosterboer HJ
P304
P356
10.1016/S0960-0760(01)00044-9
P577
2001-01-01T00:00:00Z