The intracellular pH-regulatory HCO3-/Cl- exchanger in the mouse oocyte is inactivated during first meiotic metaphase and reactivated after egg activation via the MAP kinase pathway.
about
HCO3(-)/Cl(-) exchange inactivation and reactivation during mouse oocyte meiosis correlates with MEK/MAPK-regulated Ae2 plasma membrane localization.Gatekeeper of pluripotency: a common Oct4 transcriptional network operates in mouse eggs and embryonic stem cellsInositol 1,4,5-trisphosphate receptor 1, a widespread Ca2+ channel, is a novel substrate of polo-like kinase 1 in eggs.Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.Mouse embryos stressed by physiological levels of osmolarity become arrested in the late 2-cell stage before entry into M phase.The physiology of bicarbonate transporters in mammalian reproduction.Cell volume regulation in mammalian oocytes and preimplantation embryos.Cortical mechanics and myosin-II abnormalities associated with post-ovulatory aging: implications for functional defects in aged eggs.Elevated intracellular pH appears in aged oocytes and causes oocyte aneuploidy associated with the loss of cohesion in mice.Na+/H+ exchange is inactivated during mouse oocyte meiosis, facilitating glycine accumulation that maintains embryo cell volume.
P2860
Q33510146-A6E3AD64-C9CD-431C-9012-F082E6EABD24Q33951013-7E7BD87A-71FA-461C-97F3-6A58B1D4AB06Q33954404-9D5F79E2-D3D3-4860-94B2-182CC399C3E2Q34800588-1E010128-FC00-4DE9-987C-132AC9964393Q35780394-82D174D8-5EBE-4FF4-9DE9-643B97D556FEQ37977412-67B75166-F790-4559-AA07-E6EAF3B51C89Q38046552-2BB4427D-C072-4031-8DE7-DECDACB2C997Q39964207-1DB1707C-7FC1-4337-AB25-DC97B5D05E4DQ41113552-9B94C7FF-BA10-4F06-B0E4-8EA35E3162DBQ48627383-AC202ABB-41B2-433A-96AE-77AAD4BB34EF
P2860
The intracellular pH-regulatory HCO3-/Cl- exchanger in the mouse oocyte is inactivated during first meiotic metaphase and reactivated after egg activation via the MAP kinase pathway.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@ast
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@en
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@nl
type
label
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@ast
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@en
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@nl
prefLabel
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@ast
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@en
The intracellular pH-regulator ...... on via the MAP kinase pathway.
@nl
P2093
P2860
P356
P1476
The intracellular pH-regulator ...... ion via the MAP kinase pathway
@en
P2093
Jennifer L Collins
Karen P Phillips
Mary Ann F Petrunewich
P2860
P304
P356
10.1091/MBC.E02-04-0242
P50
P577
2002-11-01T00:00:00Z