Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. - Wikidata - wikimedia - TriplyDB

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.

http://www.wikidata.org/entity/Q34276391

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The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis.Physiological and pathological implications of 5-hydroxymethylcytosine in diseases Stem Cell Models to Investigate the Role of DNA Methylation Machinery in Development of Neuropsychiatric Disorders Common stemness regulators of embryonic and cancer stem cells Mammalian epigenetic mechanisms Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing CpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signals Targeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethality Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center.Etiology of Obesity Over the Life Span: Ecological and Genetic Highlights from Asian Countries.CGGBP1 mitigates cytosine methylation at repetitive DNA sequences.Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation.Fatty acid-binding protein FABP4 mechanistically links obesity with aggressive AML by enhancing aberrant DNA methylation in AML cells.Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein.Repression of retrotransposal elements in mouse embryonic stem cells is primarily mediated by a DNA methylation-independent mechanism.Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components.Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis Application of genetic/genomic approaches to allergic disorders.Molecular and enzymatic profiles of mammalian DNA methyltransferases: structures and targets for drugs.Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei.In vivo stabilization of the Dnmt1 (cytosine-5)- methyltransferase protein Identification of preferential target sites for human DNA methyltransferases.Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state.Epigenetic susceptibility factors for prostate cancer with aging.Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylatio DNA hypermethylation in Drosophila melanogaster causes irregular chromosome condensation and dysregulation of epigenetic histone modifications.Comparative methylomics between domesticated and wild silkworms implies possible epigenetic influences on silkworm domestication.DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation.Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks.Genetics and epigenetics of obesity.Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation.A novel role for DNA methyltransferase 1 in regulating oocyte cytoplasmic maturation in pigs Epigenetic regulation of fetal bone development and placental transfer of nutrients: progress for osteoporosis Functional cooperation between HP1 and DNMT1 mediates gene silencing.Connections between epigenetic gene silencing and human disease.

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Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.

http://www.wikidata.org/entity/Q34276391

description

2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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MCB.22.7.2124-2135.2002

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Molecular and Cellular Biology

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Dnmt1 overexpression causes ge ...... ting, and embryonic lethality.

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Bernard Ramsahoye

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David Humpherys

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Detlev Biniszkiewicz

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François Gaudet

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Joost Gribnau

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Jörn Walter

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Kevin Eggan

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Mary-Ann Mastrangelo

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Zhan Jun

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P2860

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

Cloning, expression and chromosome locations of the human DNMT3 gene family

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

A modified and improved method for bisulphite based cytosine methylation analysis

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

Cancer epigenetics comes of age

Role for DNA methylation in genomic imprinting

Transcription of IAP endogenous retroviruses is constrained by cytosine methylation

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2124-2135

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7

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Rudolf Jaenisch

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11477773

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